Multi-functional membrane selective layers by interfacial free radical polymerization

通过界面自由基聚合制备多功能膜选择性层

• 批准号: 1703549
• 负责人: Ayse Asatekin
• 金额: $ 36.43万
• 依托单位: Tufts University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-06-01 至 2022-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1703549&HistoricalAwards=false
• 关键词: Multi; functional; membrane; selective; layers

1703549 AsatekinMembranes form a permeable barrier, allowing select molecules to pass into a product stream while retaining unwanted compounds. Membrane technology is crucial for purification of many substances, including water treatment, production of biological products, and food and beverage processing. Despite this diversity of applications, commercial membranes are currently made of only a handful of polymer chemistries, leaving an opportunity for development of materials that may provide greater selectivity or higher throughput, thereby increasing productivity of the purification. Of particular interest are hydrogel polymers, which unlike conventional polymers, are hydrophilic, and this opens up new applications and may increase performance by decreasing membrane fouling. The aim of this project is to develop a new, scalable method for forming thin hydrogel membranes that can incorporate a broad range of chemistries and functional nanomaterials, enabling greater productivity in purification of water and biomaterials.This project will develop an approach to form very thin, defect-free hydrophilic selective layers on membranes by free-radical interfacial polymerization. The interfacial tension between an aqueous and organic layer creates a uniform and continuous interface for polymerization. Water-soluble monomers will be polymerized by an initiator with limited aqueous solubility, which will control the thickness of the film. A range of multi-functional materials will be used to control selectivity. Design principles for a robust and scalable process will be established via variation of monomer concentration, chemistry, and polymerization conditions. Embedded functional groups will anchor integrated bio-templated catalytic nanoparticles, which will be for simultaneous deactivation of contaminants. All resulting materials will be characterized and tested for selectivity and catalytic deactivation. The project will impact polymer and membrane science, nanobiotechnology, and catalytically functionalized materials. The new materials will enable efficient water treatment and environmental cleanup. The PI and co-PI will mentor graduate students, incorporate this research in their teaching and into core lab classes, and design new outreach activities and videos for the general public that feature key aspects of the research.

1703549 Asatekin 膜形成渗透屏障，允许选定的分子进入产品流，同时保留不需要的化合物。膜技术对于许多物质的纯化至关重要，包括水处理、生物制品生产以及食品和饮料加工。尽管应用多种多样，但商业膜目前仅由少数聚合物化学物质制成，这为开发可提供更大选择性或更高通量的材料提供了机会，从而提高纯化生产率。特别令人感兴趣的是水凝胶聚合物，与传统聚合物不同，它是亲水性的，这开辟了新的应用，并且可以通过减少膜污染来提高性能。该项目的目的是开发一种新的、可扩展的方法来形成薄水凝胶膜，该方法可以包含广泛的化学物质和功能性纳米材料，从而提高水和生物材料净化的生产率。该项目将开发一种形成非常薄的水凝胶膜的方法，通过自由基界面聚合在膜上形成无缺陷的亲水选择性层。水层和有机层之间的界面张力为聚合创造了均匀且连续的界面。水溶性单体将通过水溶性有限的引发剂进行聚合，这将控制薄膜的厚度。一系列多功能材料将用于控制选择性。将通过改变单体浓度、化学和聚合条件来建立稳健且可扩展工艺的设计原则。嵌入的官能团将锚定集成的生物模板催化纳米粒子，这将用于同时使污染物失活。所有所得材料都将进行表征并测试选择性和催化失活。该项目将影响聚合物和膜科学、纳米生物技术和催化功能化材料。新材料将实现高效的水处理和环境净化。 PI 和 co-PI 将指导研究生，将这项研究纳入他们的教学和核心实验室课程，并为公众设计新的推广活动和视频，以展示该研究的关键方面。

项目成果

Triple Emulsion-Based Rapid Microfluidic Production of Core–Shell Hydrogel Microspheres for Programmable Biomolecular Conjugation

基于三重乳液的快速微流体生产核壳水凝胶微球，用于可编程生物分子共轭

• DOI: 10.1021/acsami.0c20081
• 发表时间: 2021-03
• 期刊: ACS Applied Materials & Interfaces
• 影响因子: 9.5
• 作者: Liu, Eric Y.;Choi, Yoon;Yi, Hyunmin;Choi, Chang
• 通讯作者: Choi, Chang

Controlling and Expanding the Selectivity of Filtration Membranes

控制和扩大过滤膜的选择性

• DOI: 10.1021/acs.chemmater.8b03334
• 发表时间: 2018-10-11
• 期刊: Chemistry of Materials
• 影响因子: 8.6
• 作者: Ilin Sadeghi;Papatya Kaner;A. Asatekin
• 通讯作者: A. Asatekin

Membranes with Thin Hydrogel Selective Layers Containing Viral-Templated Palladium Nanoparticles for the Catalytic Reduction of Cr(VI) to Cr(III)

含有病毒模板钯纳米颗粒的薄水凝胶选择性层膜，用于催化将 Cr(VI) 还原为 Cr(III)

• DOI: 10.1021/acsanm.9b01099
• 发表时间: 2019-07
• 期刊: ACS Applied Nano Materials
• 影响因子: 5.9
• 作者: Sadeghi, Ilin;Liu, Eric Y.;Yi, Hyunmin;Asatekin, Ayse
• 通讯作者: Asatekin, Ayse

A Robust Fabrication Technique for Hydrogel Films Containing Micropatterned Opal Structures via Micromolding and an Integrated Evaporative Deposition-Photopolymerization Approach

通过微成型和集成蒸发沉积-光聚合方法构建包含微图案蛋白石结构的水凝胶薄膜的稳健制造技术

• DOI: 10.1021/acs.langmuir.0c02983
• 发表时间: 2021-02
• 期刊: Langmuir
• 影响因子: 3.9
• 作者: Bukenya, Maurice;Lee, Jun Hyuk;Kalidindi, Subhash;DeCortin, Michael;Tice, Lauren;Yoo, Pil J.;Yi, Hyunmin
• 通讯作者: Yi, Hyunmin

High-throughput double emulsion-based microfluidic production of hydrogel microspheres with tunable chemical functionalities toward biomolecular conjugation

基于高通量双乳液的微流体生产水凝胶微球，具有可调节化学功能以实现生物分子共轭

• DOI: 10.1039/c7lc01088e
• 发表时间: 2018-01
• 期刊: Lab on a Chip
• 影响因子: 6.1
• 作者: Liu, Eric Y.;Jung, Sukwon;Weitz, David A.;Yi, Hyunmin;Choi, Chang
• 通讯作者: Choi, Chang