GOALI: Single droplet level understanding of phase inversion emulsification to enable continuous processing

GOALI：单液滴水平了解转相乳化以实现连续加工

• 批准号: 1604536
• 负责人: Daeyeon Lee
• 金额: $ 33.82万
• 依托单位: University of Pennsylvania
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-01 至 2021-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1604536&HistoricalAwards=false
• 关键词: GOALI; Single; droplet; level; understanding

CBET - 1604536PI: Lee, DaeyeonEmulsions are composed of liquid drops that are suspended in an immiscible liquid, such as oil drops in water. The drops are the dispersed phase, and the immiscible liquid is the continuous phase. Emulsions are used in the manufacture of many products, including foodstuffs, nutrients, drugs, and pesticides. Phase inversion emulsification (PIE) is a process for generating a new emulsion by inverting the phases of an existing emulsion. PIE is especially useful when it is difficult to generate the desired emulsion by other methods. For example, Xerox uses PIE to manufacture latex particles, which are used to produce toners for printing and photocopying. This GOALI project, which is a collaborative effort between the University of Pennsylvania and Xerox, will explore a variation on PIE called flow-induced PIE. In flow-induced PIE, phase inversion takes place by flowing an existing emulsion through microchannels that contain abrupt variations in their cross-sections, such as constrictions or expansions. Under proper conditions, an emulsion of oil drops in water flowing through the channel is inverted into an emulsion of water drops in oil. Experiments will be designed to explore effects of channel geometry, flow rates, wettability of the channel surface, and composition of the liquid phases on the phase inversion process. The flow-induced PIE process will allow products to be manufactured in a continuous process with reduced energy consumption, higher efficiency, and reduced environmental impact. The project will provide opportunities for students at various academic levels to participate in research. Students from underrepresented groups will be encouraged to participate through several programs at Penn, including the Louis Stokes Alliance for Minority Participation.A series of experiments will be conducted to determine effects of initial emulsion morphology and chemistry as well as channel geometry on the mechanism and efficiency of flow-induced PIE. The effect of surface wettability of the channels on the phase inversion process will be determined. Hydrodynamic parameters such as shear and extensional deformation in the microchannels will also be examined. The use of a microfluidic platform will enable the formation of model emulsions with controlled properties and the direct observation of PIE during flow. Emulsion droplets with precisely controlled size, size distribution and interfacial chemistry will be used to understand effects of emulsion morphology and chemistry on flow-induced PIE. Alternative arrangements that can promote flow-induced PIE will also be explored, including flow through a microfluidic device containing pillar arrays, which serves as a model porous medium.

CBET - 1604536PI：Lee，Daeyeon 乳液由悬浮在不混溶液体中的液滴组成，例如水中的油滴。液滴是分散相，不混溶的液体是连续相。乳液用于制造许多产品，包括食品、营养品、药物和农药。转相乳化 (PIE) 是通过反转现有乳液的相来生成新乳液的过程。 当通过其他方法难以生成所需乳液时，PIE 特别有用。例如，施乐公司使用 PIE 来制造乳胶颗粒，用于生产打印和复印用的墨粉。 这个 GOALI 项目是宾夕法尼亚大学和 Xerox 之间的合作项目，将探索 PIE 的一种变体，称为流诱导 PIE。 在流动诱导 PIE 中，通过使现有乳液流过横截面突然变化（例如收缩或扩张）的微通道来发生相转化。在适当的条件下，流过通道的水中油滴乳液转化为油中水滴乳液。 将设计实验来探索通道几何形状、流速、通道表面的润湿性以及液相组成对相转化过程的影响。流动诱导的 PIE 工艺将使产品能够以连续工艺制造，从而降低能耗、提高效率并减少对环境的影响。 该项目将为不同学术水平的学生提供参与研究的机会。将鼓励来自代表性不足群体的学生参与宾夕法尼亚大学的多个项目，包括路易斯斯托克斯少数民族参与联盟。将进行一系列实验，以确定初始乳液形态和化学以及通道几何形状对机制和效率的影响流引起的PIE。 将确定通道表面润湿性对相转化过程的影响。 还将检查微通道中的剪切和拉伸变形等流体动力学参数。 微流体平台的使用将能够形成具有受控特性的模型乳液，并在流动过程中直接观察 PIE。具有精确控制尺寸、尺寸分布和界面化学的乳液液滴将用于了解乳液形态和化学对流动诱导 PIE 的影响。还将探索可以促进流动诱导 PIE 的替代布置，包括流经包含柱阵列的微流体装置，该微流体装置充当模型多孔介质。