CAREER: SusChEM: Iron Catalysts for the Reduction of Amides

职业：SusChEM：用于还原酰胺的铁催化剂

• 批准号: 1554906
• 负责人: Michael Findlater
• 金额: $ 50万
• 依托单位: Texas Tech University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-07-15 至 2021-09-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1554906&HistoricalAwards=false
• 关键词: CAREER; SusChEM; Iron; Catalysts; Reduction

In this project funded by the Chemical Synthesis program of the Chemistry Division, Professor Michael Findlater of the Department of Chemistry at Texas Tech University is developing sustainable catalysts based upon the earth abundant transition metals. Chemical catalysis is used to produce many commodity chemicals in the pharmaceutical, construction, communication and food industries and thus, is a fundamental economic driver for the U.S. economy. However, many of the most importance catalytic transformations rely on expensive and rare metal elements. These rare metals currently provide a critical need in catalytic chemistry. To meet this challenge, new catalysts based on less toxic and earth abundant elements are being designed and synthesized as replacements for the precious metal elements currently in use. An outreach program developed by Professor Findlater involves the development of traveling Labs which focus on catalysis. The labs are designed for portability to allow transport to rural area high schools; allowing the students the means to learn about catalysis. This project focuses on new environmentally benign catalysts based on diimine complexes of iron, as well as the study of the varied mechanisms at play in iron catalysis. Various catalyst structures are being examined, and the most promising ones are being studied further using X-ray crystallography, paramagnetic NMR spectroscopy, Mössbauer spectroscopy and detailed kinetic analyses. The broader impacts of this work include potential societal benefits from the discovery of catalysts from less toxic, earth abundant metals and new insight into the reaction chemistry of first-row transition metals.

在化学部化学综合计划资助的该项目中，得克萨斯理工大学化学系的迈克尔·芬特莱特（Michael Findlater）教授正在根据地球丰富的过渡金属开发可持续的催化剂。化学催化用于在药品，建筑，通信和食品工业中生产许多商品化学品，因此是美国经济的基本经济驱动力。但是，许多最进口的催化转化都取决于昂贵且稀有的金属元素。这些稀有金属目前在催化化学方面提供了关键需求。为了应对这一挑战，正在设计和合成基于毒性和地球丰富元素的新催化剂，以替代当前使用的贵金属元素。 Findlater教授制定的外展计划涉及着专注于催化的旅行实验室的发展。这些实验室的设计旨在可移植性，以便允许运输到农村地区高中；允许学生有学习催化的方法。该项目着重于基于铁的二胺复合物以及对铁催化中各种机制的研究。正在研究各种催化剂结构，并使用X射线晶体学，顺磁NMR光谱，Mössbauer光谱和详细的动力学分析进一步研究了最有希望的结构。这项工作的更广泛影响包括从毒性较小，地球丰富的金属中发现催化剂以及对第一行过渡金属反应化学的新见解的潜在社会益处。