CAREER: SusChEM: Iron Catalysts for the Reduction of Amides

职业：SusChEM：用于还原酰胺的铁催化剂

• 批准号: 2146728
• 负责人: Michael Findlater
• 金额: $ 50万
• 依托单位: University of California - Merced
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2146728&HistoricalAwards=false
• 关键词: CAREER; SusChEM; Iron; Catalysts; Reduction

In this project funded by the Chemical Synthesis program of the Chemistry Division, Professor Michael Findlater of the Department of Chemistry at Texas Tech University is developing sustainable catalysts based upon the earth abundant transition metals. Chemical catalysis is used to produce many commodity chemicals in the pharmaceutical, construction, communication and food industries and thus, is a fundamental economic driver for the U.S. economy. However, many of the most importance catalytic transformations rely on expensive and rare metal elements. These rare metals currently provide a critical need in catalytic chemistry. To meet this challenge, new catalysts based on less toxic and earth abundant elements are being designed and synthesized as replacements for the precious metal elements currently in use. An outreach program developed by Professor Findlater involves the development of traveling Labs which focus on catalysis. The labs are designed for portability to allow transport to rural area high schools; allowing the students the means to learn about catalysis. This project focuses on new environmentally benign catalysts based on diimine complexes of iron, as well as the study of the varied mechanisms at play in iron catalysis. Various catalyst structures are being examined, and the most promising ones are being studied further using X-ray crystallography, paramagnetic NMR spectroscopy, Mössbauer spectroscopy and detailed kinetic analyses. The broader impacts of this work include potential societal benefits from the discovery of catalysts from less toxic, earth abundant metals and new insight into the reaction chemistry of first-row transition metals.

在这个由化学系化学合成项目资助的项目中，德克萨斯理工大学化学系教授 Michael Findlater 正在开发基于地球丰富的过渡金属的可持续催化剂，化学催化用于生产制药中的许多商品化学品。 、建筑、通讯和食品行业，因此是美国经济的基本经济驱动力。然而，许多最重要的催化转化依赖于昂贵的稀有金属元素，这些稀有金属目前提供了关键需求。为了应对这一挑战，人们正在设计和合成基于毒性较低且地球丰富的元素的新型催化剂，以替代目前使用的贵金属元素。实验室的设计便于携带，方便学生前往农村地区的高中学习催化作用；该项目重点研究基于铁的二亚胺络合物的新型环保催化剂。正在研究各种催化剂结构，并利用 X 射线晶体学、顺磁核磁共振波谱、穆斯堡尔谱和详细的动力学分析进一步研究最有前景的催化剂结构。包括从毒性较小、地球丰富的金属中发现催化剂所带来的潜在社会效益，以及对第一行过渡金属反应化学的新见解。