Molecular-mimicking Self-assembly of Inorganic Nanoparticles Tethered with Charged Block Copolymers
带电嵌段共聚物束缚无机纳米粒子的分子模拟自组装
基本信息
- 批准号:1505839
- 负责人:
- 金额:$ 29.97万
- 依托单位:
- 依托单位国家:美国
- 项目类别:Standard Grant
- 财政年份:2015
- 资助国家:美国
- 起止时间:2015-07-01 至 2018-06-30
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Professor Zhihong Nie from the University of Maryland-College Park is being supported by the Macromolecular, Supramolecular and Nanochemistry (MSN) Program in the Chemistry Division to develop a deeper understanding of the interactions between nanoparticles. Nanoparticles (with diameters less than 1000th of that of a human hair) have properties that differ in important and useful ways from those of the corresponding bulk material. However, to realize the full potential of nanotechnology, it is essential to be able to arrange nanoparticles in specific two- and three-dimensional patterns that can enhance their properties or even provide new properties. By controlling such interactions, it may well be possible to cause nanoparticles to self-organize into desired two- and three-dimensional patterns that would open the door to new applications in chemistry, physics, biology, and other sciences. The broader impacts of the proposed research program involve training students particularly from under-represented groups to acquire skills and knowledge in nanoparticles, as well as outreach activities including mentoring economically disadvantaged high school students, organizing one-day STEM event for academically advanced 7-10th grade students, and writing informative web-based articles for educating the general public. This proposed work seeks to create a new class of hybrid building blocks and to assemble them as molecular mimics into hierarchically-ordered nanostructures. The functionalization of nanoparticles with charged polymers encodes the nanoparticles with assembly instructions, thus guiding the self-assembly of nanoparticles at multiple hierarchical levels in a step-wise fashion. This project will use a combination of computational and experimental methods to gain a fundamental understanding of how to program the interactions between nanoparticles and to control the properties of assembled nanoparticles. The assembled nanostructures could find applications in such areas as metamaterials, coatings, sensors, medicine, and optoelectronics.
马里兰州大学公园的张尼教授在化学部门的大分子,超分子和纳米化学(MSN)计划的支持下,以对纳米颗粒之间的相互作用有更深入的了解。纳米颗粒(直径少于人头发的直径少于1000个)具有与相应的大量材料的重要和有用方式不同的特性。但是,要实现纳米技术的全部潜力,必须能够以特定的两维模式来安排纳米颗粒,从而增强其特性甚至提供新的特性。 通过控制这种相互作用,很可能有可能导致纳米颗粒自组织为所需的二维模式,这将为化学,物理,生物学和其他科学领域的新应用打开大门。拟议的研究计划的更广泛的影响涉及培训学生,特别是从代表性不足的群体中培训学生,以获取纳米粒子的技能和知识,以及包括指导经济贫困的高中生的宣传活动,为学术上高级的7至10年级的STEM活动,为7至10年级的学生组织一日的STEM活动,并为基于网络的知识网络撰写知识的网络,以教育一般公众。 这项拟议的工作旨在创建一个新的混合构建块,并将它们作为分子模仿组装成层次订购的纳米结构。带有带电聚合物的纳米颗粒的功能化用装配指令编码纳米颗粒,从而以逐步的方式引导多个层次级别的纳米颗粒的自组装。该项目将使用计算和实验方法的组合来获得对如何编程纳米颗粒之间的相互作用并控制组装纳米颗粒的性质的基本理解。组装的纳米结构可以在诸如超材料,涂料,传感器,药物和光电子的区域中找到应用。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Zhihong Nie其他文献
Centimeter-Scale Superlattices of Three-Dimensionally Orientated Plasmonic Dimers with Highly Tunable Collective Properties
具有高度可调集体特性的三维定向等离子体二聚体的厘米级超晶格
- DOI:
10.1021/acsnano.1c11219 - 发表时间:
2022 - 期刊:
- 影响因子:17.1
- 作者:
Shunsheng Ye;Huaining Zha;Yifan Xia;Wenhao Dong;Fan Yang;Chenglin Yi;Jing Tao;Xiaoxue Shen;Dong Yang;Zhihong Nie - 通讯作者:
Zhihong Nie
Engineering heterogeneity of precision nanoparticles for biomedical delivery and therapy
用于生物医学递送和治疗的精密纳米颗粒的工程异质性
- DOI:
10.1002/viw.20200067 - 发表时间:
2021-05 - 期刊:
- 影响因子:8.6
- 作者:
Di Zheng;Kuikun Yang;Zhihong Nie - 通讯作者:
Zhihong Nie
Effects of thermal therapy combined with pamidronate disodium on pain associated with bone metastases: A randomized control trial (RCT) study
热疗法联合帕米膦酸二钠对骨转移相关疼痛的影响:一项随机对照试验 (RCT) 研究
- DOI:
- 发表时间:
2017 - 期刊:
- 影响因子:0
- 作者:
Fanlei Kong;Zhihong Nie;Zhongpo Liu;Shibin Hou;J. Ji - 通讯作者:
J. Ji
New insights into the effect of interparticle friction on the critical state friction angle of granular materials
颗粒间摩擦对颗粒材料临界态摩擦角影响的新见解
- DOI:
10.1016/j.compgeo.2019.103105 - 发表时间:
2019-09 - 期刊:
- 影响因子:5.3
- 作者:
Jian Gong;Jinfeng Zou;Lianheng Zhao;Liang Li;Zhihong Nie - 通讯作者:
Zhihong Nie
Fourier-shape-based reconstruction of rock joint profile with realistic unevenness and waviness features
基于傅里叶形状的岩石节理剖面重建,具有真实的不均匀性和波纹度特征
- DOI:
10.1007/s11771-019-4239-8 - 发表时间:
2019-11 - 期刊:
- 影响因子:4.4
- 作者:
Zhihong Nie;Xiang Wang;Dong-liang Huang;Lian-heng Zhao - 通讯作者:
Lian-heng Zhao
Zhihong Nie的其他文献
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{{ truncateString('Zhihong Nie', 18)}}的其他基金
Collaborative Research: An Enzyme-free Amplification Technique for Ultrasensitive ELISA of Disease Biomarkers
合作研究:疾病生物标志物超灵敏 ELISA 的无酶扩增技术
- 批准号:
1804742 - 财政年份:2018
- 资助金额:
$ 29.97万 - 项目类别:
Standard Grant
Design and self-assembly of amphiphilic supracolloidal analogues of bimolecular and trimolecular compounds
双分子和三分子化合物的两亲性超胶体类似物的设计和自组装
- 批准号:
1808689 - 财政年份:2018
- 资助金额:
$ 29.97万 - 项目类别:
Standard Grant
NSF/FDA Scholar-in-Residence at FDA: Understanding the Bioactivity and Safety of Metal and Metal Oxide Nanoparticles Used in Medical Devices
NSF/FDA 驻 FDA 学者:了解医疗器械中使用的金属和金属氧化物纳米颗粒的生物活性和安全性
- 批准号:
1541654 - 财政年份:2016
- 资助金额:
$ 29.97万 - 项目类别:
Standard Grant
CAREER: Biomimetic Self-assembly of Polymer-inorganic Hybrid Nanocompartments with Biomedical Delivery Applications
职业:聚合物-无机混合纳米室的仿生自组装与生物医学输送应用
- 批准号:
1255377 - 财政年份:2013
- 资助金额:
$ 29.97万 - 项目类别:
Continuing Grant
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