CHS: Small: Collaborative Research: Human-computer interaction for personal genomics: understanding, informing, and empowering users

CHS：小型：协作研究：个人基因组学的人机交互：理解、告知和授权用户

• 批准号: 1422706
• 负责人: Oded Nov
• 金额: $ 15.48万
• 依托单位: New York University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1422706&HistoricalAwards=false
• 关键词: CHS; Small; Collaborative; Research; Human

This project will explore the roles human-computer interaction can play in helping non-experts to understand and engage with their personal genomic information. Recent years are seeing a dramatic growth in the scale and scope of personal genomic information that is available to non-experts, often online and in interactive forms. As a result, individuals are confronted with unprecedented amounts of sensitive and often complex information about themselves, which influences their decisions, emotional states and well-being. Consequently, questions about how people make sense of and engage with their personal genomic information, and how comfortable they feel about sharing it in order to advance scientific and biomedical research, are not only of paramount importance for life sciences researchers and policy makers, but also a pressing issue for human-computer interaction researchers. Because the technology that enables lay people to interact with such information is new, there is little research on it. Given the tremendous growth in the scale and scope of genomic information available to non-experts, this work has the potential to make an impact on human-computer interaction theory and practice by investigating fundamental issues concerning non-expert interaction with complex scientific information and the impact of user interface design interventions on learning from, and sharing of, personal genomic information. Advances in five areas will be sought: (1) Functional requirements for supporting meaningful engagement of non-experts with personal genomic information; (2) Fundamental knowledge of how user interface design interventions impact users' willingness to share personal genomic data; (3) Novel interaction techniques for presenting and exploring rich, complex, and highly personalized data sets by non-experts; (4) Design guidelines for effective interaction with personal genomic information, and (5) Methodology for evaluating the effectiveness of techniques for interaction with personal genomic information.

该项目将探讨人机交互在帮助非专家理解和参与其个人基因组信息方面可以发挥的作用。 近年来，非专家可以通过在线和交互式形式获取的个人基因组信息的规模和范围急剧增长。 因此，个人面临着前所未有的大量敏感且往往复杂的关于自己的信息，这些信息影响着他们的决策、情绪状态和幸福感。 因此，关于人们如何理解和利用他们的个人基因组信息，以及他们对分享这些信息以推进科学和生物医学研究的舒适程度的问题，不仅对于生命科学研究人员和政策制定者来说至关重要，而且对于人机交互研究人员面临的一个紧迫问题。由于使外行人能够与此类信息交互的技术是新的，因此对此的研究很少。 鉴于非专家可获得的基因组信息的规模和范围的巨大增长，这项工作有可能通过研究非专家与复杂科学信息交互的基本问题和对人机交互理论和实践产生影响。用户界面设计干预对学习和共享个人基因组信息的影响。 将寻求五个领域的进展：（1）支持非专家有意义地参与个人基因组信息的功能要求； (2) 了解用户界面设计干预如何影响用户共享个人基因组数据的意愿的基础知识； (3) 新颖的交互技术，用于由非专家呈现和探索丰富、复杂和高度个性化的数据集； (4) 与个人基因组信息有效交互的设计指南，以及 (5) 评估与个人基因组信息交互的技术有效性的方法。