MRI: Development of Multifunctional CARS (Coherent Anti-Stokes Raman Spectroscopy) Imaging System

MRI：多功能CARS（相干反斯托克斯拉曼光谱）成像系统的开发

• 批准号: 1126208
• 负责人: Yongfeng Lu
• 金额: $ 26.65万
• 依托单位: University of Nebraska-Lincoln
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2014-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1126208&HistoricalAwards=false
• 关键词: MRI; Development; Multifunctional; CARS; Coherent

The objective of this Major Research Instrumentation (MRI) award is to develop a versatile, multifunctional coherent anti-Stokes Raman spectroscopy (CARS) imaging system that will be capable of nondestructive and noninvasive measurement for nanoscience, biology, and medical research with 3D confocality and nanoscale resolutions. The project will integrate morphology characterization, microscale CARS-based multimodal nonlinear optical imaging and tip-enhanced CARS imaging capabilities in a single system. Deliverables include a multi-functional CARS system, documentation of research results, and engineering student education.If successful, the results of this project will create a key equipment in a core facility that serves as a cross-disciplinary and multi-organization research and education platform in the region. The instrument will support education for graduate and undergraduate students for a diverse group of people, including women and underrepresented minority students. The successful development of this instrument will open many research opportunities in nanoscience/technology, material science, cellular biology and other fields in the United States. Graduate and undergraduate students will benefit through involvement in the research and classroom instruction. The engagement of K-12 students and teachers in this project will also establish new partnerships between the University and K-12 schools.

这项主要研究仪器奖（MRI）奖的目的是开发一种多功能的，多功能的相干反stokes Raman光谱（CARS）成像系统，该系统将能够对纳米科学，生物学和医学研究进行无创和非侵入性测量，并具有3D共磁和纳米级分辨率。该项目将整合形态表征，基于微观汽车的多模式非线性光学成像和单个系统中的尖端增强汽车成像功能。可交付成果包括多功能汽车系统，研究结果的文档以及工程学生的教育。如果成功，该项目的结果将在核心设施中创建一个关键设备，该设施是该地区的跨学科和多组织研究和教育平台。该工具将为包括妇女和代表性不足的少数族裔学生在内的各种各样的人群为研究生和本科生提供教育。该工具的成功开发将为美国的纳米科学/技术，材料科学，细胞生物学和其他领域的许多研究机会开放。研究生和本科生将通过参与研究和课堂教学而受益。 K-12学生和教师参与该项目的参与也将在大学和K-12学校之间建立新的合作伙伴关系。