Engineering Polymers for Stem-Cell-Fate Regulation and Regenerative Medicine

用于干细胞命运调节和再生医学的工程聚合物

• 批准号: 1104752
• 负责人: Sandra DeVincent Wolf
• 金额: $ 0.8万
• 依托单位: Materials Research Society
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-04-01 至 2012-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1104752&HistoricalAwards=false
• 关键词: Engineering; Polymers; Stem; Cell; Fate

ID: MPS/DMR/BMAT(7623) 1104752 PI: S. Wolf/S. Heilshorn ORG: Gordon Conf/Stanford UTitle: Engineering Polymers for Stem-Cell-Fate Regulation and Regenerative MedicineINTELLECTUAL MERIT: This proposal will support travel awards for graduate students, post-docs, and underrepresented and junior faculty to attend and present at a 2.5-day symposium on Engineering Polymers for Stem-Cell-Fate Regulation and Regenerative Medicine at the Spring Materials Research Society National Meeting in San Francisco, CA, April 25-29, 2011. The broad focus of the symposium is to assess how the recent advances in molecular design, synthesis, and micro and nano-scale fabrication of polymeric materials can be integrated with stem cell biology to develop new strategies in stem cell-based therapies and regenerative medicine. In particular, the emphasis will be placed on using novel technologies in polymer science and engineering to control both biochemical and biophysical signals, to regulate these signals in space and time, and to investigate stem cell behavior and fate in such engineered microenvironments and their implications for regenerative medicine. BROADER IMPACTS:The objective of this symposium is to define an inclusive community of researchers with interdisciplinary perspectives working at the intersection of polymer science, engineering, and stem cell biology toward the goal of revolutionizing stem cell-based therapies over the coming decade. Thus, the broader impacts of this project are to initiate exchange of ideas and promote new multi-disciplinary collaborations among materials scientists, life scientists, engineers, and clinicians. The project will also enable junior scientists, including graduate students, postdoctoral scholars, and junior faculty, particularly those in underrepresented groups, to present their research findings and to interact with the community of established researchers in this field. The event will also publicize recent advances in the design and synthesis of polymeric biomaterials and their use in both fundamental discovery-driven stem cell biology and applied regenerative medicine therapies.

ID：MPS/DMR/BMAT（7623）1104752 PI：S。Wolf/s。 Heilshorn ORG: Gordon Conf/Stanford UTitle: Engineering Polymers for Stem-Cell-Fate Regulation and Regenerative MedicineINTELLECTUAL MERIT: This proposal will support travel awards for graduate students, post-docs, and underrepresented and junior faculty to attend and present at a 2.5-day symposium on Engineering Polymers for Stem-Cell-Fate Regulation and Regenerative Medicine at the Spring Materials Research Society National Meeting在2011年4月25日至29日，在加利福尼亚州旧金山。研讨会的广泛重点是评估如何将分子设计，合成以及微细胞材料的微型和纳米级制造的最新进展与干细胞生物学整合在一起，以开发基于干细胞的疗法和基于干细胞疗法和再生药物的新策略。 特别是，将重点放在使用聚合物科学和工程中的新技术来控制生物化学和生物物理信号，以在时空中调节这些信号，并在这种工程的微环境中调查干细胞行为和命运及其对再生药物的影响。更广泛的影响：该研讨会的目的是定义一个包容性的研究人员社区，其跨学科的观点在聚合物科学，工程和干细胞生物学相交的跨学科观点上，以在未来十年中革新基于干细胞的治疗的目标。 因此，该项目的更广泛的影响是启动思想交流，并促进材料科学家，生命科学家，工程师和临床医生之间的新的多学科合作。 该项目还将使包括研究生，博士后学者和初级教师，尤其是代表人数不足的教职员工，以介绍他们的研究结果并与该领域的知名研究人员互动。 该活动还将宣传聚合物生物材料的设计和合成的最新进展及其在基本发现驱动的干细胞生物学和应用再生医学疗法中的使用。