SBIR Phase II: Innovations in Nanoscale Manufacturing: Nanomaterial Composites for Dental Restorations

SBIR 第二阶段：纳米制造创新：用于牙科修复的纳米材料复合材料

• 批准号: 1057826
• 负责人: Joseph Bringley
• 金额: $ 50万
• 依托单位: TRANSPARENT MATERIALS, LLC
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-02-01 至 2014-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1057826&HistoricalAwards=false
• 关键词: SBIR; Phase; II; Innovations; Nanoscale

This Small Business Innovation Research (SBIR) Phase II project seeks to develop nanomanufacturing methods for producing nanocomposites for use in dentistry. Nanocomposites have shown great promise in dentistry but have limited applications because of the lack of reliable manufacturing methods to prepare them at scale. This Phase II project seeks to develop a new, highly-efficient and low-cost approach to the manufacture of these materials that allows their assembly from the individual components at the nanoscale. The process produces highly homogeneous nanomaterials with increased functionality. These materials simultaneously have multiple property enhancements such as radiopacity (aiding diagnostic capabilities), high strength and durability, and improved optical properties. This technology can be further leveraged to expand market opportunities into adjacent segments where cost constraints have limited the adoption of advanced nanocomposites.The broader impact/commercial potential of this project is to provide nanomaterial composites that improve the function of dental restorations and of biomedical implants. The technology is anticipated to facilitate medical implant materials that better integrate into the human body, improve durability and use-life, and aid diagnosis, ultimately reducing the rate of revision procedures and improving patient outcomes. In the context of dental restoratives, these materials offer improved aesthetics, enhanced radiopacity for diagnostics, and state-of-the art strength and durability. The development and maturation of the proposed products will have significant impact upon the dental industry, allowing dentists to better diagnose recurrent caries, which will improve clinical outcomes and ultimately reduce the occurrence of clinical revision/replacement procedures. The cost savings associated with the new process will increase access of the general public to the highest quality dental restorations.

该小型企业创新研究 (SBIR) 第二阶段项目旨在开发纳米制造方法，用于生产牙科用纳米复合材料。纳米复合材料在牙科领域显示出巨大的前景，但由于缺乏可靠的制造方法来大规模制备纳米复合材料，其应用受到限制。 该第二阶段项目旨在开发一种新的、高效且低成本的方法来制造这些材料，从而允许它们在纳米级上由各个组件组装而成。 该工艺生产出具有增强功能的高度均质的纳米材料。 这些材料同时具有多种性能增强功能，例如射线不透性（有助于诊断能力）、高强度和耐用性以及改进的光学性能。 可以进一步利用该技术将市场机会扩大到成本限制限制了先进纳米复合材料采用的相邻领域。该项目更广泛的影响/商业潜力是提供改善牙齿修复和生物医学植入物功能的纳米材料复合材料。该技术预计将促进医疗植入材料更好地融入人体，提高耐用性和使用寿命，并帮助诊断，最终降低翻修手术的速度并改善患者的治疗效果。 在牙科修复材料中，这些材料提供了更好的美观性、增强的诊断射线不透性以及最先进的强度和耐用性。 拟议产品的开发和成熟将对牙科行业产生重大影响，使牙医能够更好地诊断复发性龋齿，这将改善临床结果并最终减少临床翻修/更换手术的发生。 新工艺节省的成本将增加公众获得最高质量牙齿修复的机会。