Pyridine-bis(oxazoline) derivatives for enhanced Ln(III) emission in aqueous systems and in the solid state

吡啶-双（恶唑啉）衍生物可增强水性系统和固态中的 Ln(III) 发射

• 批准号: 1058805
• 负责人: Ana de Bettencourt-Dias
• 金额: $ 38.4万
• 依托单位: Board of Regents, NSHE, obo University of Nevada, Reno
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-15 至 2015-01-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=1058805&HistoricalAwards=false
• 关键词: Pyridine; bis; oxazoline; derivatives; enhanced

With this award, the Chemical Synthesis Program is funding Professor Ana de Bettencourt-Dias at the University of Nevada-Reno to synthesize and study the photophysics of new derivatized pyridine-bis(oxazoline) (Pybox) lanthanide complexes. While Pybox ligands have been extensively used in transition-metal catalyzed organic synthesis, it was only recently that their ability to efficiently sensitize lanthanide ion luminescence was reported. In particular, the project seeks to establish a structure-function relationship of Pybox ligands with respect to sensitization of lanthanide ion luminescence. Moreover, water-soluble complexes are being targeted for use in bioluminescence, as are complexes that can be incorporated into polymers, for solid state lighting applications.As noted above, this project has potential long-term scientific broader impacts in the areas of bioimaging and solid state materials. Moreover, research in lanthanide ion chemistry is potentially connected with the chemistry of actinides, as lanthanide complexes are sometimes used as surrogates to mimic the chemistry of the radioactive actinides. Educational broader impacts include the training of undergraduate, graduate and postdoctoral co-workers in a multidisciplinary environment, including elements of synthetic organometallic chemistry and ofabsorption, excitation and emission spectroscopy.

通过此奖项，化学合成计划正在内华达大学 - 里诺大学（University of Nevada-Reno）资助Ana de Bettencourt-Dias教授，以合成和研究新的衍生化吡啶双基（恶唑啉）（Pybox）灯笼型腺苷酸复合物的光体物理学。 尽管PYBOX配体已被广泛用于过渡金属催化的有机合成，但直到最近，它们才有有效敏感的灯笼离子发光的能力。 特别是，该项目试图建立pybox配体与灯笼离子发光敏化的结构 - 功能关系。 此外，水溶性复合物是用于生物发光的目标，可以将可以掺入聚合物的复合物，用于固态照明应用中。如上所述，该项目在生物影像和固态材料领域具有潜在的长期科学广泛影响。此外，在灯笼离子化学方面的研究可能与肌动剂的化学有关，因为有时将兰烷化复合物用作模仿放射性actacinides的化学性质的替代物。 教育更广泛的影响包括在多学科环境中对本科，研究生和博士后同事的培训，包括合成有机金属化学和剂量，激发和发射光谱的元素。