EAGER: Ultraminiature Imaging Systems for Biomedical Applications

EAGER：用于生物医学应用的超小型成像系统

基本信息

批准号：
1053204
负责人：
Armand Tanguay,Jr.
金额：
$ 30万
依托单位：
University of Southern California
依托单位国家：
美国
项目类别：
Standard Grant
财政年份：
2010
资助国家：
美国
起止时间：
2010-09-01 至 2013-08-31
项目状态：
已结题

来源：
https://www.nsf.gov/awardsearch/showAward?AWD_ID=1053204&HistoricalAwards=false
关键词：
EAGER Ultraminiature Imaging Systems Biomedical

项目摘要

1053204TanguayThe fundamental goal of this potentially transformative research project is to investigate the feasibility of ultracompact optical imaging systems for ultraminiature cameras designed for chronic surgical implantation in the human body, as well as for minimally invasive endoscopic examinations. Biomedical imaging applications of such ultraminiature cameras include chronically implantable cameras, ultraminiature endoscopes, an intraocular camera for retinal prostheses, a wide field-of-view eye-tracked extraocular camera for retinal prostheses, and a miniaturized eyetracking camera.The principal research activities enabled by this grant will include theoretical analysis, fabrication, and test of ultraminiature optical systems that are both compact and low-mass to allow for surgical implantation; the incorporation of optimized imaging capability in such highly miniaturized optical systems by means of ultra-small form factor refractive and hybrid refractive/diffractive optical elements; the investigation of design principles for the development of low power, low form factor CMOS image sensor arrays that are optimized for biomedical imaging applications, and the assessment by means of visual psychophysics techniques of the importance of pre- and post-image filtering of pixellated images for biomedical applications, in order to establish appropriate design constraints for these novel optical imaging systems.

1053204TAGUAY这个潜在的转化研究项目的基本目标是调查针对人体中慢性手术植入的超显影摄像机的超型光学成像系统的可行性，以及微创内窥镜检查。此类超显影相机的生物医学成像应用包括慢性植入式相机，超显影性内窥镜，一种用于视网膜假体的眼内摄像机，广泛的视野视野外摄像机，用于视网膜假期的视网膜外摄像头，以及该批准的批准及其对批准的批准。既紧凑又低质量的光学系统，以允许手术植入；通过超小型外形折射率和杂化折射/衍射光学元件，将优化成像能力融合在这种高度微型化的光学系统中；针对生物医学成像应用优化的低功率，低功率CMOS图像传感器阵列的设计原理的调查，以及通过视觉心理物理学的评估，以对生物医学应用的贴生和后图像过滤的重要性进行生物医学图像的重要性，以建立这些新颖的设计构造，以建立适当的设计构造。