CAREER: Deterministic and stochastic transport of suspended particles in periodic systems: fundamentals and applications in separation sciences.

职业：周期性系统中悬浮颗粒的确定性和随机传输：分离科学的基础知识和应用。

• 批准号: 0954840
• 负责人: German Drazer
• 金额: $ 41.5万
• 依托单位: Johns Hopkins University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-01-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0954840&HistoricalAwards=false
• 关键词: CAREER; Deterministic; stochastic; transport; suspended

0954840DrazerThe research goal is to develop an integrated research and education program dedicated to investigate the complex transport phenomena that arises in the motion of suspended particles in spatially periodic systems, as well as the translation of these phenomena into new principles for the manipulation of suspended particles in fluidic devices. The objective is to develop a unified description of the deterministic and stochastic transport of individual particles as they move through spatially periodic systems in both single phase and two phase systems.The proposed fundamental studies will provide the foundations for the rational design of novel microfluidic separation devices, that go beyond the miniaturization of macroscopic methods, and fully exploit the dominant physical phenomena at small scales, such as Brownian motion and colloid surface interactions. To harness these complex phenomena we will take advantage of the superior control provided by current fabrication techniques to determine the geometrical structure and surface chemistry of planar microfluidic devices. The strategy is to create specific periodic patterns that dictate the behavior of the suspended particles by inducing spatial partitioning on individual species and/or controlling non linear hydrodynamic effects, and/or by creating selective surface-particle interactions and/or by directing their Brownian motion. In this project we investigate a challenging problem in the area of transport phenomena in particulate systems. That is, understanding the deterministic and stochastic behavior of suspended colloids in periodic systems that have anisotropic and heterogeneous properties. Contributions to this field could impact a broad range of disciplines, from a better understanding of colloid enhanced transport of pollutants in underground water reservoirs, to making progress in traditional analytical methods such as volume averaging techniques. The results will also impact the growing area of lab on a chip devices, which promises to revolutionize the chemical sciences, by providing novel methods to manipulate suspended species.The project will integrate research and education with the development of web based virtual experiments on particle transport in microfluidic devices. The labs will give the users an exciting look into state of the art developments in engineering. At the same time, the labs will provide a platform to understand key concepts in transport phenomena. A second aspect of the integration between research and education is the design of simple experiments that demonstrate the fundamental phenomena that control the transport in microfluidic systems, but at a macroscopic scale. Specifically, we are developing experiments on the sedimentation of steel balls in planar, transparent, periodic porous media fabricated from LEGO pieces.

0954840DRAZER研究目标是开发一项综合研究和教育计划，该计划致力于研究空间周期性系统中悬浮颗粒运动的复杂运输现象，以及将这些现象转化为流体设备中悬浮颗粒的新原理。 The objective is to develop a unified description of the deterministic and stochastic transport of individual particles as they move through spatially periodic systems in both single phase and two phase systems.The proposed fundamental studies will provide the foundations for the rational design of novel microfluidic separation devices, that go beyond the miniaturization of macroscopic methods, and fully exploit the dominant physical phenomena at small scales, such as Brownian motion and colloid surface interactions.为了利用这些复杂的现象，我们将利用当前制造技术提供的优越控制，以确定平面微流体设备的几何结构和表面化学。该策略是创建特定的周期性模式，通过对单个物种诱导空间划分和/或控制非线性流体动力效应和/或通过引起选择性的表面粒子相互作用和/或指导其布朗尼运动来决定悬浮颗粒的行为。在这个项目中，我们研究了颗粒系统中运输现象领域的一个具有挑战性的问题。也就是说，了解具有各向异性和异质性质的周期性系统中悬浮胶体的确定性和随机行为。从对胶体增强地下水库中污染物的运输的更好理解到在传统的分析方法（例如体积平均技术）中取得进展，对这一领域的贡献可能会影响广泛的学科。结果还将通过提供操纵悬浮物种的新方法来影响芯片设备上实验室的生长区域，该芯片设备有望改变化学科学。该项目将与基于Web的微流体设备中基于Web的虚拟粒子传输的虚拟实验整合。实验室将使用户令人兴奋地看待工程领域的最先进的发展。同时，实验室将提供一个平台来了解运输现象中的关键概念。研究与教育之间整合的第二个方面是简单实验的设计，这些实验证明了控制微流体系统中运输的基本现象，但以宏观的规模。具体而言，我们正在开发有关用乐高积木制造的平面，透明，周期性多孔介质在平面，透明的周期性多孔介质中进行沉降的实验。