SGER: Innovative Fabrication of Microporous Surfaces With Nano-Roughness on Titanium Biomedical Implants

SGER：在钛生物医学植入物上创新制造具有纳米粗糙度的微孔表面

• 批准号: 0733522
• 负责人: Sreeramamurthy Ankem
• 金额: $ 8.2万
• 依托单位: University of Maryland, College Park
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-15 至 2008-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0733522&HistoricalAwards=false
• 关键词: SGER; Innovative; Fabrication; Microporous; Surfaces

The project to be carried out at the University of Maryland, College Park deals with innovative fabrication of microporous surfaces with nano-roughness on biomedical titanium implants. Present biomedical implants such as hip joints have low longevity of 10 to 15 years. One of the primary reasons for low longevity is poor interfacial bonding strength between the implant and the bone. This project addresses this problem by creating controlled microporous surfaces with nano-roughness on titanium implant materials so that bone can grow onto these surfaces thereby significantly increasing the interlocking. The specific goals include fabrication of microporous surfaces by carving out from the titanium surface by innovative plasma processing techniques. Further the microporous surfaces will be nano-roughened either by plasma techniques or polymerization techniques.This project has outstanding broader impacts. A successful completion of this project will result in new, untested fabrication techniques to improve interlocking, increasing the strength of the implant-bone interfaces. When these techniques are adapted to current biomedical implants, the longevity of the implants can be significantly increased beyond the current limit of 10 to 15 years. This will greatly improve the quality of life and at the same time reduce health care costs. Further, a graduate student will be trained in this project adding to the pool of scientists who can carry out further research in this direction and/or help the biomedical implant industry.

该项目将在马里兰州大学进行，大学公园与生物医学钛植入物上的纳米粗糙度进行了微孔表面的创新制造。 当前的生物医学植入物（例如髋关节）的寿命较低10至15年。 寿命较低的主要原因之一是植入物和骨骼之间的界面粘结强度差。 该项目通过在钛植入物材料上创建具有纳米粗糙度的受控微孔表面来解决此问题，从而使骨头可以在这些表面上生长，从而显着增加互锁。 具体目标包括通过创新的等离子体加工技术从钛表面划出微孔表面。 此外，微孔表面将通过等离子体技术或聚合技术来纳米脉冲。该项目具有更大的广泛影响。 该项目的成功完成将导致新的未经测试的制造技术来改善互锁，从而提高植入物骨接口的强度。 当这些技术适应当前的生物医学植入物时，植入物的寿命可以显着增加超过目前10到15年的限制。 这将大大提高生活质量，同时降低医疗保健成本。 此外，将在该项目中对研究生进行培训，并增加了可以在这个方向上进行进一步研究和/或帮助生物医学植入工业的科学家库。