Collaborative Research: DRU: Behavioral and Neural Effects of Sleep Deprivation on Specific Components of Decision Making

合作研究：DRU：睡眠剥夺对决策特定组成部分的行为和神经影响

• 批准号: 0727794
• 负责人: David Dickinson
• 金额: $ 6.95万
• 依托单位: Appalachian State University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-05-01 至 2011-04-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0727794&HistoricalAwards=false
• 关键词: Collaborative; Research; DRU; Behavioral; Neural

Abstract Project Summary Collaborative Research: DRU: Behavioral and Neural Effects of Sleep Deprivation on Specific Components of Decision Making Drummond,Sean University of California-San Diego This research combines efforts from the fields of sleep, cognitive neuroscience, and experimental economics. This project will examine the impact of multiple types of sleep deprivation on specific components of decision making. The research will examine changes in behavioral performance and brain function during decision after sleep deprivation. A well-controlled laboratory-based sleep deprivation study will examine both 26 hours of total sleep deprivation (no sleep at all) and 6 nights of partial sleep deprivation (some, but insufficient, sleep each night) relative to a well-rested condition. Subjects will perform decision tasks designed to assess a) risk preference, b) information integration, c) probability weighting, and d) value processing during decision making. Brain function during performance will be measured with functional magnetic resonance imaging. To determine the extent to which these laboratory findings can be generalized to the type of sleep deprivation experienced in the ?real world?, the PIs will conduct studies at two separate undergraduate institutions. These two studies will objectively track the sleep (and other factors) of a relatively large number of undergraduates for a week each and then administer the decision tasks. Students at these schools average 4-7 hours of sleep each night. By studying an ecologically natural range of sleep times outside the laboratory, one can determine if this type of sleep loss produces similar behavioral changes (and presumably, brain function changes) as seen in the laboratory. These experiments recreate fundamental tasks that are at the very core of countless real-world decisions, such as financial or medical decisions or evaluating environmental risks. Together, the three studies will provide rich information concerning the effects of sleep deprivation on decision making and seek to directly evaluate the extent to which laboratory-controlled findings can generalize to a real-world model of sleep deprivation.

摘要项目摘要合作研究：DRU：睡眠剥夺对制定Drummond的特定组成部分的行为和神经影响，加利福尼亚肖恩大学迭戈分校这项研究结合了睡眠，认知神经科学和实验经济学领域的努力。该项目将研究多种类型的睡眠剥夺对决策的特定组成部分的影响。该研究将检查睡眠剥夺后决策期间行为表现和大脑功能的变化。基于实验室的基于实验室的睡眠剥夺研究将检查26个小时的全部睡眠剥夺（根本没有睡眠）和6晚的部分睡眠剥夺（有些但不足，每晚不足，每晚睡眠）相对于良好的状况。受试者将执行旨在评估的决策任务a）风险偏好，b）信息整合，c）概率加权和d）在决策过程中的价值处理。性能过程中的大脑功能将通过功能磁共振成像来测量。为了确定这些实验室发现可以推广到现实世界中经历的睡眠剥夺类型的程度，PI将在两个独立的本科机构进行研究。这两项研究将客观地跟踪一个相对较大的本科生的睡眠（和其他因素），每周一周，然后管理决策任务。这些学校的学生平均每晚4-7个小时的睡眠。通过研究实验室以外的生态自然睡眠时间，可以确定这种类型的睡眠损失是否会产生类似的行为变化（大概是大脑功能变化），如实验室所见。这些实验重新制定了无数现实决定的核心，例如财务或医疗决策或评估环境风险。这三项研究将共同​​提供有关睡眠剥夺对决策的影响的丰富信息，并试图直接评估实验室控制的发现可以推广到现实的睡眠剥夺模型的程度。