RUI: Experimental and Theoretical Investigation into the Reactions of Atomic Carbon with Organic Substrates

RUI：原子碳与有机底物反应的实验和理论研究

• 批准号: 0719335
• 负责人: Dasan Thamattoor
• 金额: --
• 依托单位: Colby College
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2010-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0719335&HistoricalAwards=false
• 关键词: RUI; Experimental; Theoretical; Investigation; into

This RUI award to Professor Dasan M. Thamattoor of the Chemistry Department at Colby College in Waterville, ME has as its goal the production of arc generated carbon atoms and the study of their reactions. Interesting divalent carbon intermediates (carbenes) will be generated by reactions with a variety of organic chemical substrates. More specifically, these organic substrates include alkenes, alkynes, azulene, acid chlorides, 1,2-dicarbonyl compounds and molecules with highly strained single carbon-carbon bonds. The chemistry of these intermediates and the pathways by which they are formed and consumed will be investigated experimentally and by modern computational techniques. The proposed work, which integrates elements of synthetic, mechanistic, and computational organic chemistry, is designed to provide undergraduates with a wholesome research experience, and enable them to make original contributions to scientific knowledge. Among the most important broader impacts of this research, as mentioned above, is the mentoring of undergraduate researchers and training them as future scientists in a predominantly undergraduate institution. A number of ideas for melding research and education, based on approaches that have already met with success, will be implemented. This is exemplified, for instance, by the incorporation of research-like projects and new pedagogical experiments in the introductory organic chemistry laboratory course. The proposal also seeks to continue Prof. Thamattoor's highly successful program that provides research opportunities to high school students over the summer months. Women, minorities, and students from disadvantaged backgrounds will also be recruited to participate in summer research activities. In addition, there will be new initiative that forges partnerships with elementary school teachers to specifically strengthen the science curriculum in the K-3 level. Finally, it is expected that a number of important fundamental chemical reaction pathways will be elucidated.

这是沃特维尔科尔比学院化学系的Dasan M. Thamattoor教授的RUI奖，它的目标是产生弧形原子及其反应的研究。 有趣的二价碳中间体（Carbenes）将通过与各种有机化学底物的反应产生。 更具体地说，这些有机底物包括烯烃，炔烃，叠氮，酸氯化物，1,2-二甲苯和具有高度应变的单个碳碳键的分子。这些中间体的化学及其形成和消耗的途径将通过实验和现代计算技术进行研究。 拟议的工作整合了合成，机械和计算有机化学的要素，旨在为大学生提供有益健康的研究经验，并使他们能够为科学知识做出原始贡献。如上所述，这项研究最重要的更广泛的影响是对本科研究人员的指导，并在主要本科机构中培训他们为未来的科学家。 基于已经成功的方法，将实施许多有关融合研究和教育的想法。例如，通过在入门有机化学实验室课程中纳入类似研究的项目和新的教学实验来说明这一点。该提案还旨在继续Thamattoor教授的非常成功的计划，该计划在夏季为高中生提供了研究机会。来自弱势背景的妇女，少数民族和学生也将被招募参加夏季研究活动。此外，还将有新的计划与小学教师建立伙伴关系，以特别加强K-3级别的科学课程。 最后，预计将阐明许多重要的基本化学反应途径。