New Monolithic Structures for Chromatography

用于色谱分析的新型整体结构

• 批准号: 0554677
• 负责人: Luis Colon
• 金额: $ 44万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0554677&HistoricalAwards=false
• 关键词: New; Monolithic; Structures; Chromatography

Professor Luis Colon of the SUNY at Buffalo is supported by the Analytical and Surface Chemistry Program in the Division of Chemistry to investigate the synthesis and characterization of a new generation of permeable monolithic structures that are based on metal oxides (e.g., ZrO2, HfO2). These monolithic structures are potentially applicable to the separation and purification of a broad spectrum of chemicals and biochemicals. Fundamental studies of the reaction conditions that lead to the final metal oxide materials, their physicochemical properties, and their chromatographic performance will be conducted. The characteristics and compositions of the synthesized materials will be assessed using a variety of spectroscopic and physical probes. These investigations are part of a long-term research program focused on the study of new and improved materials with applicability in chemical analysis, particularly in chromatographic separations. This research project will contribute to the education and training of graduate and undergraduate students, including members of traditionally underrepresented groups, in the synthesis and characterization of monolithic structures and in chromatographic separation and analysis methods.HPLC continues to be an indispensable analytical tool that facilitates advances in the chemical, biological, pharmaceutical, medicinal, food, and agricultural sciences. The development of chromatographic materials that withstand harsh and extreme pH conditions could lead to improved chromatographic separations and broaden the scope of applicability of the technique.

纽约州立大学布法罗分校的 Luis Colon 教授在化学系分析和表面化学项目的支持下，研究基于金属氧化物（例如 ZrO2、HfO2）的新一代可渗透整体结构的合成和表征。 这些整体结构可能适用于广泛的化学品和生物化学品的分离和纯化。将对最终金属氧化物材料的反应条件、其物理化学性质及其色谱性能进行基础研究。 合成材料的特性和成分将使用各种光谱和物理探针进行评估。 这些研究是长期研究计划的一部分，该计划的重点是研究适用于化学分析（特别是色谱分离）的新材料和改进材料。 该研究项目将有助于研究生和本科生（包括传统上代表性不足群体的成员）在整体结构的合成和表征以及色谱分离和分析方法方面的教育和培训。HPLC 仍然是促进进步的不可或缺的分析工具化学、生物、制药、医学、食品和农业科学。 开发能够承受恶劣和极端 pH 条件的色谱材料可以改善色谱分离并扩大该技术的适用范围。