Studies of New Materials for Separations

新分离材料的研究

• 批准号: 9614947
• 负责人: Luis Colon
• 金额: $ 42万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-12-15 至 2002-02-28
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9614947&HistoricalAwards=false
• 关键词: Studies; New; Materials; Separations

This project, directed by Assistant Professor Luis A. Colon at SUNY-Buffalo, is supported by the Analytical and Surface Chemistry Program in the Division of Chemistry. The work will use sol-gel technology to synthesize chemically bonded stationary phases for use with chromatographic methods, particularly high performance liquid chromatography (HPLC) and electrochromatography in open and packed columns. The incorporation of the desired functional groups into the sol-gel reagents during the fabrication of the silica will create Si-C bonds that do not undergo hydrolysis and provide a material that is multilayered. These characteristics are especially promising for solving the existing problem of suitable packing and surfaces for separations at high pH. Studies will be done of the variables affecting the chemical reactions involved in the glass formation process. A number of techniques (ESCA, SIMS, FTIR and others) will be used to examine the physicochemical properties of the glasses, followed by examination of the chromatographic performance. The overall objective is to correlate the processing parameters, the material characteristics and the separation performance. Liquid chromatographic methods are powerful techniques to separate complex mixtures of compounds into their individual constituents. The purpose of this work is to provide an entirely new way to synthesize the materials upon which the separation takes place. Applications of such separations are wide-spread in areas such as environmental analysis, pharmaceutical analysis, and many others. The focus of the project is to make materials with properties superior to those now available.

该项目由纽约州立大学布法罗分校助理教授 Luis A. Colon 指导，并得到化学系分析和表面化学项目的支持。 这项工作将使用溶胶-凝胶技术合成化学键合固定相，用于色谱方法，特别是开式和填充柱中的高效液相色谱 (HPLC) 和电色谱。 在二氧化硅的制造过程中将所需的官能团掺入溶胶-凝胶试剂中将产生不发生水解的Si-C键，并提供多层材料。 这些特性对于解决高 pH 下分离的合适填料和表面的现有问题特别有希望。将研究影响玻璃形成过程中涉及的化学反应的变量。 将使用多种技术（ESCA、SIMS、FTIR 等）来检查玻璃的物理化学性质，然后检查色谱性能。 总体目标是将加工参数、材料特性和分离性能关联起来。 液相色谱方法是将复杂的化合物混合物分离成各自成分的强大技术。 这项工作的目的是提供一种全新的方法来合成发生分离的材料。 这种分离的应用广泛应用于环境分析、药物分析等领域。 该项目的重点是制造性能优于现有材料的材料。