NMR Spectroscopy as a Cornerstone Technique in the Undergraduate Chemical Curriculum

核磁共振波谱作为本科化学课程的基石技术

• 批准号: 0310901
• 负责人: Kevin Shaughnessy
• 金额: $ 12.07万
• 依托单位: University of Alabama Tuscaloosa
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-01 至 2006-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0310901&HistoricalAwards=false
• 关键词: NMR; Spectroscopy; Cornerstone; Technique; Undergraduate

Chemistry (12) Nuclear Magnetic Resonance (NMR) is a powerful technique for structural determination and quantification that is widely used across all areas of science. In the traditional undergraduate curriculum, hands-on experience with NMR is typically limited outside of sophomore organic classes. This project uses NMR as a cornerstone technique in nine undergraduate laboratory classes. In additional to traditional uses of NMR to identify and characterize structures in organic and inorganic chemistry, NMR is being used to demonstrate principles in analytical, physical chemistry, and biochemistry labs. The specific goal of this project is to improve student understanding of chemical principles, by using NMR as a cornerstone technique, with which students become proficient over their career. To achieve our goals of expanding NMR beyond the sophomore organic lab, we are using a modern, high-field NMR spectrometer. The new instrument is used in a hands-on fashion by both chemistry majors and non-majors taking sophomore through senior level chemistry lab classes. Published experiments, primarily from the Journal of Chemical Education, are being adapted and integrated within the nine courses in order to achieve our curricular goals. A tutorial page is used to walk students through the transfer and processing of a standard NMR data file, with the processing system modeled on one used at Florida State University. Finally, a workshop is being offered annually to regional four-year institutions that are interested in having student samples run on our NMR. The results are e-mailed back to the students who then use software capable of all standard NMR processing functions to analyze their data.Intellectual Merit: The use of technology in the classroom is of increasing importance to teach modern scientific concepts and engage computer literate students. NMR is a central technique since it can be used to study a variety of problems. This project is leading to the development of a number of new laboratory experiments, and these experiments will be made available to other instructors interested in increasing the use of NMR in their laboratory classes. Broader Impact: The proposed project is involving approximately 300 undergraduate students per year. These students receive hands-on experience as a means to learn fundamental chemical concepts. We also expect that students will be excited about chemistry, and science in general, as a result of this project. In particular, by reaching out to non-majors we hope to encourage these students, particularly those from under-represented groups, to consider careers in the sciences.

化学（12）核磁共振（NMR）是一种用于结构确定和定量的强大技术，可在所有科学领域广泛使用。 在传统的本科课程中，NMR的动手经验通常受到大二有机课程之外的限制。 该项目将NMR用作九个本科实验室课程中的基石技术。 在NMR传统用途的其他方面，用于识别和表征有机和无机化学中的结构，NMR被用来展示分析，物理化学和生物化学实验室中的原理。 该项目的具体目标是通过将NMR用作基石技术来提高学生对化学原理的理解，并熟练地熟练自己的职业生涯。 为了实现我们将NMR扩展到大二有机实验室之外的目标，我们正在使用现代的高场NMR光谱仪。化学专业和非裁判均通过高级化学实验室课程将新仪器以动手方式使用。 已发布的实验主要来自《化学教育杂志》，正在对九门课程进行调整和整合，以实现我们的课程目标。 教程页面用于引导学生完成标准NMR数据文件的转移和处理，并以佛罗里达州立大学使用的处理系统进行了模型。 最后，每年为有兴趣在我们的NMR上运行学生样本的地区四年机构提供研讨会。 结果将通过电子邮件发送给学生，然后他们使用能够使用所有标准NMR处理功能的软件来分析其数据。IntlectualFure：在课堂上使用技术对教授现代科学概念并吸引计算机知识学生的重要性越来越重要。 NMR是一种中心技术，因为它可用于研究各种问题。 该项目导致了许多新的实验室实验的发展，这些实验将提供给有兴趣增加NMR在其实验室类别中使用的其他教师。更广泛的影响：拟议的项目每年涉及大约300名本科生。 这些学生获得动手经验，以此作为学习基本化学概念的一种手段。 我们还希望，由于这个项目，学生将对化学和一般科学感到兴奋。 特别是，通过与非硕士接触，我们希望鼓励这些学生，尤其是来自代表性不足的团体的学生，以考虑科学中的职业。