Acquisition of a Nanoparticle Analysis Ensemble

获得纳米颗粒分析套件

• 批准号: 0079612
• 负责人: Theodore Randolph
• 金额: $ 19.25万
• 依托单位: University of Colorado at Boulder
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至 2002-08-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0079612&HistoricalAwards=false
• 关键词: Acquisition; Nanoparticle; Analysis; Ensemble

CTS-0079612Theodore W. RandolphUniversity of ColoradoMRI: Acquisition of a Nanoparticle Analysis EnsembleAbstractThis grant supports the purchase of a group of instruments that provide the capability of analysis and characterization of various types of microparticles and nanoparticles. One instrument , a Quantachrome Autosorb 1-C, is a multipurpose device for determining surface areas and pore-size distributions as well as surface-site properties by gas adsorption/desorption methods. A second, a ZetaPlus, can measure zeta potential on particles from colloidal size up to 30-microns diameter. This device has a phase-analysis light-scattering option that increases the sensitivity of electrophoretic mobility measurements. A third acquisition is an Aerosizer DSP dry powder size analyzer, with supersonic gas entrainment of particles combined with laser optics, which can measure particle-size distributions from 0.2 to 700 microns. The last item in the ensemble is a TSI GEMMA-method size analyzer. This device creates an aerosol of suspended particles, dries the droplets, and then measures mobility of the remaining particles in an electric field. The lower limit on size measurement here corresponds to a protein molecule with molecular weight of 6000.Nanotechnology promises advances in many practical fields. The researchers using these instruments for characterization of nanoparticles are exploring applications in high-temperature synthesis of new ceramic materials, gene therapy, controlled drug delivery, protein stabilization in powders, production and treatment of nanoparticulate materials, and biotechnology. The availability of these highly sensitive measurement instruments increases the accuracy and precision of their observations and enhances the significance of their results.

CTS-0079612Theodore W. Randolph 科罗拉多大学 MRI：收购纳米粒子分析整体摘要这笔赠款支持购买一组能够分析和表征各种类型的微粒和纳米粒子的仪器。 Quantachrome Autosorb 1-C 是一种多功能设备，用于通过气体吸附/解吸方法测定表面积和孔径分布以及表面位点特性。 第二种是 ZetaPlus，可以测量从胶体尺寸到直径 30 微米的颗粒的 zeta 电位。 该设备具有相位分析光散射选项，可提高电泳迁移率测量的灵敏度。 第三项收购是 Aerosizer DSP 干粉粒度分析仪，具有超音速气体夹带颗粒与激光光学器件相结合，可测量 0.2 至 700 微米的粒度分布。 整体中的最后一项是 TSI GEMMA 方法尺寸分析仪。 该设备产生悬浮颗粒的气溶胶，干燥液滴，然后测量电场中剩余颗粒的迁移率。 这里尺寸测量的下限对应于分子量为 6000 的蛋白质分子。纳米技术有望在许多实际领域取得进步。 研究人员使用这些仪器来表征纳米颗粒，正在探索在新型陶瓷材料的高温合成、基因治疗、受控药物输送、粉末中的蛋白质稳定、纳米颗粒材料的生产和处理以及生物技术中的应用。 这些高灵敏度测量仪器的可用性提高了观测的准确性和精密度，并增强了结果的重要性。