POWRE: Self-Assembling Cyclic Ureas

POWRE：自组装环脲

• 批准号: 9973132
• 负责人: Linda Shimizu
• 金额: $ 7.49万
• 依托单位: University of South Carolina at Columbia
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-12-01 至 2002-05-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9973132&HistoricalAwards=false
• 关键词: POWRE; Self; Assembling; Cyclic; Ureas

The research is focused on the synthesis and characterization of hollow tubular nano-structures formed by hydrogen bonding interactions between amide and carbonyl groups of macrocyclic monomers, each of which contains two urea units linked to form a donut shaped building block. The Y linker units in (-YHNCONH-)2 contain aromatic rings to keep the cyclic monomers planar, and can be chosen to provide a variety of tube dimensions and hydrophobicities. Based on known molecular structures, the repeat distance between donuts is expected to be 4.61 Angstroms. The tubes, which are expected to self-assemble in solution, will be characterized by proton and carbon NMR, STM, and x-ray diffraction. With this POWRE award the Chemistry Division supports the work of Linda S. Shimizu in the Department of Chemistry and Biochemistry at the University of South Carolina in Columbia, SC. The proposed research will explore the synthesis and characterization of hollow organic tubes of controlled molecular dimensions which are expected to find uses as ion and small molecule transport devices, sensors and catalysts.

这项研究的重点是由酰胺和大环单体的羰基之间的氢键相互作用形成的空心管状纳米结构的合成和表征，每个均包含两个尿素单元，这些尿素单元链接在一起形成甜甜圈形的构建块。 （-yhnconh-）2中的Y连接器单元包含芳族环以保持环状单体平面，并且可以选择以提供各种管尺寸和疏水性。 基于已知的分子结构，甜甜圈之间的重复距离预计为4.61埃。 预期在溶液中自组装的管将以质子和碳NMR，STM和X射线衍射为特征。 通过此POWRE奖，化学部支持了南卡罗来纳州南卡罗来纳大学的化学和生物化学系Linda S. Shimizu的工作。 拟议的研究将探讨受控分子尺寸的空心有机管的合成和表征，这些管有望找到用作离子和小分子传输设备，传感器和催化剂的用途。