Self-Assembled Organic Nanotubes from Cyclic Ureas

环脲自组装有机纳米管

• 批准号: 0316424
• 负责人: Linda Shimizu
• 金额: $ 21.3万
• 依托单位: University South Carolina Research Foundation
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-08-01 至 2006-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=0316424&HistoricalAwards=false
• 关键词: Self; Assembled; Organic; Nanotubes; Cyclic

The focus of this research is the synthesis and study of a series of macrocycles that consist of urea groups linked by rigid spacers. The hydrogen bonding interactions between the cyclic urea monomers drives their self-assembly into tubular structures that contain sizeable homogeneous tubular channels. A number of analytical, biochemical and physical chemistry methods will be used to evaluate the success of these assembled nanotubes. Materials with tubular channels are sought for applications as sensors, templates for directed reactions, and in ion and small molecule transport systems. With this new award, the Organic and Macromolecular Chemistry Program is supporting the research and educational efforts of Dr. Linda Shimizu of the Department of Chemistry and Biochemistry at the University of South Carolina, Columbia, where she is a Research Assistant Professor. Dr. Shimizu will focus her research on tubular assemblies, which have recently been shown to have antibacterial properties. Undergraduate and graduate students trained in this program will receive a broad multidisciplinary background that will empower them to pursue a wide range of scientific careers. This award also supports the enhancement and continuation of the chemistry outreach program that fosters interactions between K-12 students and teachers and skilled scientific researchers.

这项研究的重点是对一系列由刚性垫片连接的尿素组组成的一系列大环的合成和研究。 环状尿素单体之间的氢键相互作用将它们的自组装驱动到包含相当均匀的管状通道的管状结构中。 许多分析，生化和物理化学方法将用于评估这些组装纳米管的成功。 寻求具有管状通道的材料作为传感器，定向反应的模板以及离子和小分子传输系统的应用。 有了这一新奖项，有机和大分子化学计划正在支持哥伦比亚南卡罗来纳大学化学和生物化学系的琳达·辛祖（Linda Shimizu）博士的研究和教育工作，她是研究助理教授。 Shimizu博士将把她的研究集中在管状组件上，最近已证明其具有抗菌特性。 在该计划中接受培训的本科生和研究生将获得广泛的多学科背景，这将使他们有能力从事广泛的科学职业。 该奖项还支持化学外展计划的增强和延续，该计划促进了K-12学生与教师以及熟练的科学研究人员之间的互动。