Career: Self-Organization of Amphiphilic Block Copolymers for the Preparation of Highly Ordered Materials: A Research and Education Program

职业：用于制备高度有序材料的两亲性嵌段共聚物的自组织：研究和教育计划

• 批准号: 9875848
• 负责人: Paschalis Alexandridis
• 金额: $ 30万
• 依托单位: SUNY at Buffalo
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-01 至 2004-11-30
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9875848&HistoricalAwards=false
• 关键词: Career; Self; Organization; Amphiphilic; Block

ABSTRACTCTS-9875848P. AlexandridisSUNYThe ability of amphiphilic molecules to organize at various configurations and lengthscales allows multiple levels of organization, often with remarkable precision. In additional to all living creatures being manifestations of such self-organization (e.g. lipid cell membranes), numerous technical products and processes that involve, e.g., surfactants and copolymers, are taking advantage of properties (compartmentalization, compatibilization, rheological) afforded by self-organization.The present investigation focuses on amphiphilic block copolymers, macromolecules consisting of hydro(solvo)philic and hydro(solvo)phobic blocks (or grafts), that are very interesting from the aspect of both formulations and materials synthesis, and offer advantages over typical surfactants. The macromolecular nature of the amphiphilic block copolymers affords great flexibility in setting the desired morphology, and allows a considerable variation of the length- and time-scales characteristic to the microstructure. An important degree of freedom (compared to "solvent-free" block copolymers) is the presence of selective solvent(s), that can modulate the phase behavior and structure, and also act as suitable media for chemical synthesis.The goals of the research are two-fold: to achieve a desired microstructure via means of self-organization of amphiphilic block copolymers and to stabilize such microstructure for the synthesis of microporous materials. To this end, it is planned to study the self-assembly of amphiphilic block copolymers under equilibrium conditions and utilize this knowledge to prepare formulations offering desired compartmentalization and release properties, use shear for aligning microdomains and inducing order over long ranges, investigate mass transport in ordered systems in the context of structure formation and dissolution, and explore the synthesis of ordered materials via the crosslinking of the amphiphiles participating in the structure or via polymerization in the solvent domains.In the education front, having recognized the fact that the pharmaceutical, personal care products, and food industries, where amphiphiles are primarily used, are emerging fields for employment of chemical engineers, it is proposed to develop a curriculum wit courses on colloids, polymers, surfaces, and advanced materials, and incorporate research term-projects into these courses and involve undergraduate students at various steps of the proposed research. On a more general level, cooperative learning and learning by objective will be introduced to all courses, with a specific interest in the Introduction to Chemical Engineering sophomore course. Outreach activities to high schools and to community colleges will aim in introducing chemical engineering as well as colloids and polymers to abroader audience. Overall, the educational plan aims in promoting creativity, providing an enriching environment for graduate and undergraduate research, and fully integrating research and educational activities.

Abstractcts-9875848p。 Alexandridissuny在各种构型和长度尺度上组织两亲分子的能力允许多个组织的组织，通常具有很高的精度。 除其他所有生物的其他生物是这种自组织（例如脂质细胞膜）的表现中，许多技术产品和过程涉及（例如表面活性剂和共聚物），它利用了属性（通过自我组织隔离，兼容，兼容，兼容，兼容），对当前的研究进行了研究。从配方和材料合成的方面，Hydro（Solvo）Philic和Hydro（Solvo）恐惧块（或移植物）非常有趣，并且比典型的表面活性剂具有优势。 两亲性块共聚物的大分子性质在设置所需的形态方面具有极大的灵活性，并允许微观结构的长度和时间尺度有很大的变化。 重要的自由度（与“无溶剂”的块共聚物相比）是选择性溶剂的存在，可以调节相位行为和结构，并且还充当适合化学合成的媒介，研究的目标是两倍：通过稳定材料的肢体构造和稳定性的材料来实现所需的微观结构。 为此，计划在平衡条件下研究两亲性块共聚物的自组装，并利用这些知识来制备提供所需的分隔和释放属性的配方，并使用剪切来对齐微区和诱导长度范围内的长度范围，并通过井层进行批量运输，并在结构上进行批量运输，并在结构上探索构建和材料的构建，并在结构上进行构建，并在结构上进行构建，并构建质量，并构建质量，并在结构上进行构建，并构建质量，并构建质量，并构建质量，并构建了质量，并构建了质量，并构建了构建和质量范围。 amphiphiles participating in the structure or via polymerization in the solvent domains.In the education front, having recognized the fact that the pharmaceutical, personal care products, and food industries, where amphiphiles are primarily used, are emerging fields for employment of chemical engineers, it is proposed to develop a curriculum wit courses on colloids, polymers, surfaces, and advanced materials, and incorporate research term-projects into these课程并让本科生参与拟议研究的各个步骤。 从更一般的层面上讲，将通过目标进行合作学习和学习，并在化学工程大二课程中特别感兴趣。向高中和社区大学的外展活动将旨在向国外观众介绍化学工程以及胶体和聚合物。总体而言，该教育计划旨在促进创造力，为研究生和本科研究提供丰富的环境，并充分整合研究和教育活动。