Purhase of a High Resolution Mass Spectrometer

购买高分辨率质谱仪

• 批准号: 9708640
• 负责人: Lawrence Barton
• 金额: $ 25万
• 依托单位: University of Missouri-Saint Louis
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9708640&HistoricalAwards=false
• 关键词: Purhase; Resolution; Mass; Spectrometer

This award from the Chemistry Research Instrumentation and Facilities (CRIF) Program and the Office of Multidisciplinary Activities (OMA) will assist the Department of Chemistry at University of Missouri at St. Louis to acquire a high resolution mass spectrometer. This equipment will enhance research in a number of areas that include the following: (1) studies on organometallic species used as polymerization catalysts, (2) synthesis and reactions of metallaborane complexes, (3) organic synthesis and development of synthetic methods, (4) natural product isolation and reactions, (5) the analysis of unstable organic oxidation products in simulated environments, and study of self-assembled monolayers derived from modified cyclodextrins. Mass spectrometry (MS) is a technique used to probe intimate structural details and to obtain the molecular compositions of a vast array of organic, bioorganic, and organometallic molecules. The addition of the technique of electrospray extends the range of MS to proteins and nucleic acid molecular weights far beyond any other technique. The use of electrospray ionization in combination with high resolution provides the latest techniques available in mass spectrometry. It affords the chemist one of the most powerful tools available for the characterization of compounds. The acquisition of this capability in mass spectrometry is essential for the prosecution of frontier research in many fields of chemistry.

该奖项由化学研究仪器和设施 (CRIF) 计划和多学科活动办公室 (OMA) 授予，将协助密苏里大学圣路易斯分校化学系购买一台高分辨率质谱仪。该设备将加强以下多个领域的研究：（1）用作聚合催化剂的有机金属物种的研究，（2）金属硼烷配合物的合成和反应，（3）有机合成和合成方法的开发，（4） ）天然产物分离和反应，（5）模拟环境中不稳定有机氧化产物的分析，以及改性环糊精衍生自组装单分子层的研究。 质谱 (MS) 是一种用于探测密切结构细节并获取大量有机、生物有机和有机金属分子的分子组成的技术。电喷雾技术的加入将 MS 的范围扩展到蛋白质和核酸分子量，远远超过任何其他技术。电喷雾电离与高分辨率的结合使用提供了质谱分析中可用的最新技术。它为化学家提供了用于表征化合物的最强大的工具之一。获得这种质谱分析能力对于许多化学领域的前沿研究的开展至关重要。