Experimental and Theoretical Studies of the Coevolution of Inbreeding Depression and Mating System

近交抑制与交配系统协同进化的实验与理论研究

• 批准号: 9707684
• 负责人: Marcy Uyenoyama
• 金额: $ 23.5万
• 依托单位: Duke University
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2001-07-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=9707684&HistoricalAwards=false
• 关键词: Experimental; Theoretical; Studies; Coevolution; Inbreeding

9707684 Uyenoyama Mating between closely related individuals often results in inbreeding depression, or the production of offspring of lower quality. This project addresses the evolution of mating systems in response to inbreeding depression and its evolution in turn in response to the mating system. Theoretical analyses suggest that the penalty of inbreeding depression evolves to different magnitudes among familial lineages that practice different levels of inbreeding. Among the possible consequences of such interactions is the evolution of mixed mating systems, which entail both inbreeding and outbreeding. Natural populations of Datura stramonium, which practices a mixed mating system, provide a model system for the direct exploration of these issues. Previous work has demonstrated that a morphological character (stigma-anther distance) is both heritable and a determinant of the level of inbreeding in individuals. The magnitude of inbreeding depression will be estimated in individual families. This system permits a test of whether inbreeding depression at the family level is associated with mating system. In addition, numerical simulation studies will be conducted to explore various aspects of associations between inbreeding depression and familial lineage, including their genetic bases and consequences for the evolution of mating systems. All living organisms are subject to the deleterious effects of mutations. Processes that influence the generation, purging, and maintenance of mutational load directly affect the length and quality of life. Theoretical and empirical studies have established mating system as a major determinant as well as a consequence of inbreeding depression in natural populations.

9707684密切相关的个体之间的uyenoyama交配通常会导致近交抑郁症或质量较低的后代产生。 该项目涉及响应近亲抑郁症及其演变的交配系统的演变，反过来响应交配系统。 理论分析表明，近亲抑郁症的惩罚会导致家族谱系中不同近亲繁殖水平的家族谱系的不同幅度。 这种相互作用的可能后果之一是混合交配系统的演变，这既需要近亲繁殖和繁殖。 实践混合交配系统的Datura Stramonium的天然种群为直接探索这些问题提供了模型系统。 先前的工作表明，形态学特征（污名化距离）既可以遗传，又是个体近亲繁殖水平的决定因素。 近亲抑郁症的大小将在个别家庭中估计。 该系统允许测试家庭一级的近交抑郁症与交配系统有关。 此外，还将进行数值模拟研究，以探索近交抑郁症和家族谱系之间关联的各个方面，包括它们的遗传基础和对交配系统演变的后果。 所有生物体都受到突变的有害影响。 影响突变负荷的产生，清除和维护的过程直接影响生活的长度和质量。 理论和实证研究已将交配系统建立为自然种群陷入繁殖抑郁的主要决定因素和结果。