Cell-adhesion mechanisms of inhibitory synapse specificity and their dysfunction in neuropsychiatric disorders

抑制性突触特异性的细胞粘附机制及其在神经精神疾病中的功能障碍

• 批准号: 488087
• 负责人: Takahashi Hideto
• 金额: $ 78.02万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-09-01 至 2028-09-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=488087&lang=en
• 关键词: Cell Adhesion; Molecular And Cellular Neuroscience; Neurobiology; Neuropsychiatric Disorder; Synapse Biology

Precise control of brain activity is crucial for normal brain function, and its dysregulation is thought to be linked with neuropsychiatric disorders such as autism. Brain cells called interneurons release a signal called GABA that inhibits their target n

脑活动的精确控制对于正常的大脑功能至关重要，并且其失调被认为与神经精神疾病（如自闭症）有关。称为中间神经元的脑细胞释放一个名为GABA的信号，该信号抑制其靶N