The role of apoB100-lipoproteins in fatty acid trapping in obese subjects; in vivo and in vitro models

apoB100-脂蛋白在肥胖受试者脂肪酸捕获中的作用；

• 批准号: 201302
• 负责人: Salem Huda
• 金额: $ 1.27万
• 依托单位: Institut de recherches cliniques de Montral
• 依托单位国家: 加拿大
• 项目类别: Studentship Programs
• 财政年份: 2010
• 资助国家: 加拿大
• 起止时间: 2010-02-01 至 2011-02-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=201302&lang=en
• 关键词: Adipose Tisue Biopsies; Clinical And Basic Research; Ex Vivo And In Vitro Models; In Vivo; Isotope Ration Mass Spectrometry; Lipoprotein Metabolism; Metabolism; Nutrition; Obesity; Stable And Radioactive Isotopes; Type 2 Diabetes

Low efficiency of dietary fat storage in fat tissue may increase the risk of type 2 diabetes. We believe that atherogenic particles that carry cholesterol in the blood (commonly known as bad cholesterol or LDL) may decrease fat storage in fat tissue in hu

脂肪组织中膳食脂肪储存效率低下可能会增加患 2 型糖尿病的风险。我们认为，血液中携带胆固醇（俗称坏胆固醇或低密度脂蛋白）的致动脉粥样硬化颗粒可能会减少人体脂肪组织中的脂肪储存。