D-Mannose Supplementation Attenuates Atherosclerotic Lesions in High Fat Diet Fed ApoE-/- Mice:  Implications of Gut Microbiota Modulation.

D-甘露糖补充剂可减轻高脂肪饮食喂养的 ApoE-/- 小鼠的动脉粥样硬化病变：肠道微生物群调节的影响。

• 批准号: 495292
• 负责人: O'Connor Miranda Jonathan A
• 金额: $ 0.11万
• 依托单位: Lady Davis Institute for Medical Research (Mtl)
• 依托单位国家: 加拿大
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-09-01 至 2024-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=495292&lang=en
• 关键词: D-Mannose

D-mannose, a natural sugar, had previously shown promise in altering gut bacteria and preventing obesity. This study focused on whether it could also combat artery-clogging atherosclerosis. In mice genetically predisposed to artery problems, D-mannose was

D-甘露糖是一种天然糖，此前曾显示出改变肠道细菌和预防肥胖的前景。这项研究的重点是它是否也可以对抗动脉阻塞的动脉粥样硬化。在遗传上易患动脉问题的小鼠中，D-甘露糖