Histone Acetylation Regulates Microglial Innate Immune Memory

组蛋白乙酰化调节小胶质细胞先天免疫记忆

• 批准号: 478927
• 负责人: Ciernia Annie V
• 金额: $ 72.73万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-03-01 至 2028-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=478927&lang=en
• 关键词: Chromatin; Enhancers; Epigenetics; Gene Regulation; Inflammation; Microglia

The immune system is made up of specialized cells that defend the body against infections. The brain also has immune cells that act as a natural defense against brain infections and injury. The immune cells in the brain, called microglia, play a role in h

免疫系统由保护身体免受感染的特殊细胞组成。大脑还具有免疫细胞，可以作为对抗大脑感染和损伤的天然防御。大脑中的免疫细胞（称为小胶质细胞）在 h 中发挥作用。