Modulation in the use of multisensory information during voluntary action

自愿行动期间多感官信息使用的调节

基本信息

批准号：
RGPIN-2020-05831
负责人：
Tremblay, Luc
金额：
$ 2.04万
依托单位：
University of Toronto
依托单位国家：
加拿大
项目类别：
Discovery Grants Program - Individual
财政年份：
2020
资助国家：
加拿大
起止时间：
2020-01-01 至 2021-12-31
项目状态：
已结题

来源：
https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=718034
关键词：
Modulation use multisensory information during

项目摘要

As you lift a water bottle and bring it over a glass, the receptors in your muscles and eyes are exposed to different excitation patterns. Lifting the bottle first requires adjusting the initial forces generated by your limb muscles, which is known as impulse regulation. After, bringing the spout over the glass requires additional adjustments, known as limb-target regulation. Although these sensorimotor processes have been discovered through studies of visual-motor functions, little is known about the contribution of muscle receptors (i.e., proprioception) to these processes. Thus, the current research program will unravel the contribution of vision and proprioception to the impulse and limb-target regulation processes. The first series of sensorimotor studies will present brief flashes of vision at different portions of a reaching movement, while employing different movement amplitudes and durations. Building upon theoretical debates about when vision is utilized during a voluntary movement, parsimonious frameworks of the different sensorimotor processes taking place during movements of different durations and amplitudes will be developed. The second series of sensorimotor studies will add visual perturbations during the brief flashes of vision. That will include moving a cloud of random dots forming a visual background and/ or a shift in target location. Because impulse regulation is thought to occur before limb-target regulation, it is expected that background perturbations will have significant effects on limb trajectories when presented early during the movement. In turn, target jumps are expected to have significant effects on limb trajectories when presented later during the movement. The third series of sensorimotor studies will incorporate a tendon vibration manipulation that is presented between trials and reduces the sensitivity of muscle receptors (i.e., proprioception). Using selected studies from the two series above, tendon vibration studies will test for the contribution of proprioception for impulse and limb-target regulation processes. As well, when combined with visual perturbations (i.e., background and/ or target), these studies will help determine if vision and proprioception are integrated for impulse and limb-target regulation. The last series will employ perceptual reports (e.g., “Did your limb final position undershot or overshot the target?”). The influence of vision and/or proprioceptive perturbations on the perceived limb endpoint are expected to corroborate the results from the sensorimotor studies. Overall, determining which sources of sensory information predominantly contribute to impulse vs. limb-target regulation will refine models of sensorimotor control. As well, these models will inform various practical designs (e.g., human-machine interfaces, rehabilitation programs and robots, sport training protocols).

当您抬起水瓶并将其放在玻璃杯上时，肌肉和眼睛中的接收器会暴露于不同的兴奋方式。首先提起瓶子需要调整肢体肌肉产生的初始力，这被称为脉冲调节。之后，将喷口放在玻璃上需要其他调整，称为肢体靶向调节。尽管这些感觉运动过程是通过对视觉运动功能的研究发现的，但对肌肉接收器（即，本体感受）对这些过程的贡献知之甚少。这是当前的研究计划将揭示视力和本体感受对脉冲和肢体目标调节过程的贡献。第一系列的感觉运动研究将在使用不同的运动放大器和持续时间的同时，在到达运动的不同部分处呈现视力闪烁。基于关于何时在自愿运动中使用视觉的理论辩论，将开发出在不同持续时间和放大器的运动中发生的不同感觉运动过程的简约框架。第二系列的感觉运动研究将在短暂的视觉闪光期间增加视觉扰动。这将包括移动一个随机点的云，形成视觉背景和/或目标位置的变化。由于脉冲调节被认为是在肢体目标调节之前发生的，因此预计背景扰动在运动早期出现时会对肢体轨迹产生重大影响。反过来，在运动后期出现时，目标跳跃预计会对肢体轨迹产生重大影响。第三系列的感觉运动研究将结合肌腱振动的操纵，该操作在试验之间呈现并降低肌肉受体的灵敏度（即，前检查）。利用上面两个系列中的选定研究，肌腱振动研究将测试脉冲和肢体靶向调节过程的本体感受的贡献。同样，当与视觉扰动（即背景和/或目标）结合使用时，这些研究将有助于确定视力和本体感受是否已整合为脉冲和肢体靶向调节。最后一个系列将采用感知报告（例如，“您的肢体最终位置是否明显或超出了目标？”）。视力和/或本体感受性扰动对感知到的肢体终点的影响有望证实感觉运动研究的结果。总体而言，确定哪些感官信息来源主要有助于冲动与肢体目标调节，将完善感觉运动控制模型。同样，这些模型将为各种实践设计（例如人机接口，康复计划和机器人，体育培训方案）提供信息。