Suberin: Biosynthesis, Form and Function

木栓质：生物合成、形式和功能

• 批准号: RGPIN-2017-04228
• 负责人: Bernards, Mark
• 金额: $ 2.33万
• 依托单位: University of Western Ontario
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=710940
• 关键词: Suberin; Biosynthesis; Form; Function

Suberin is an unusual plant polymer. It gives root and tuber tissue a “corky” barrier against water loss and protects against disease organisms. In addition, new suberin is formed during wound-healing. In this context, suberin deposition serves to seal exposed tissues. Wound suberin also prevents water loss and disease. Suberin's protective roles make it interesting to crop breeders. It represents a source of natural resistance to disease, drought and salt stress. However, there is little direct evidence for the wide spread role of suberin as a protective substance. Two aspects of suberin remain poorly understood. The physical structure of the polymer, and the control of suberin biosynthesis and deposition. This lack of knowledge inhibits further exploration of this remarkable polymer as a natural plant defense. This proposal will (1) increase understanding of the biosynthesis, deposition and structure of suberin, and (2) demonstrate its broad effect as a protective barrier against pathogens. Upon completion we will be able to manipulate suberin levels through conventional breeding. This will lead to new crop varieties with enhanced, natural defenses against the pathogens that reduce food product yields. It will also lead to new crop varieties with enhanced tolerance to drought and salt stress.

Suberin是一种不寻常的植物聚合物。它使根和块茎组织成为防水损失的“软木”屏障，并防止疾病生物。此外，在伤口愈合期间形成了新的suberin。在这种情况下，Suberin沉积物可密封暴露的组织。伤口suberin还可以防止水流失和疾病。 Suberin的受保护角色使作物育种者变得有趣。它代表了对疾病，干旱和盐胁迫的自然抵抗来源。但是，几乎没有直接证据表明suberin作为保护物质的广泛传播作用。 Suberin的两个方面仍然知之甚少。聚合物的物理结构，以及链蛋白生物合成和沉积的控制。缺乏知识阻碍了对这种非凡聚合物作为天然植物防御的进一步探索。该建议将（1）增加对suberin的生物合成，沉积和结构的理解，（2）表明其作为对病原体的受保护屏障的广泛作用。完成后，我们将能够通过常规育种来操纵suberin水平。这将导致新的农作物品种，以增强自然防御能力，以减少食品产量的病原体。这还将导致新的作物品种，对干旱和盐胁迫的耐受性增强。