Design, characterize and validate a new multifunctional coating, with antiviral and antibacterial properties for COVID-19 pandemic

设计、表征和验证一种新型多功能涂层，具有针对 COVID-19 大流行的抗病毒和抗菌特性

• 批准号: 551375-2020
• 负责人: Momen, Gelareh
• 金额: $ 3.64万
• 依托单位: Université du Québec à Chicoutimi
• 依托单位国家: 加拿大
• 项目类别: Alliance Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=702505
• 关键词: Design; characterize; validate; new; multifunctional

Viruses are among the most harmful pathogens to the human population and are responsible for the death of millions of people every year. In 2019, a cluster of pneumonia cases in Wuhan City, Hubei Province, China were identified as a novel beta coronavirus, and the disease it caused was termed coronavirus disease 2019 (COVID-19). COVID-19 has quickly evolved into a global pandemic in just over two months. U.N. Secretary-General Antonio Guterres believes that the world faces the most challenging crisis since World War II, confronting a pandemic threatening people in every country that probably has no parallel in the recent past. The COVID-19 transmission could be mitigable with physical and chemical sanitization, such as spraying or wiping. However, sanitization is labor- and materials-intensive, impractical for covering all exposed areas, and needs to be reapplied periodically. Therefore, it will be useful to develop the self-sanitizing surfaces that can slowly release disinfecting chemicals to mitigate fomite transmission. Such coatings should be durable against rubbing and washing, long-lasting, and nontoxic and should be easily applied on the surfaces of already-installed objects that people frequently touch. This project targets to explore multifunctional antibacterial and antiviral coating through an encapsulated alkaline solution incorporated in a superhydrophobic coating. This coating can effectively improve antibacterial/antiviral performance over the long term, can guarantee the suitable release of bactericide and virucidal agents over time, and can consequently strongly impair the risk of COVID-19 diseases.

病毒是对人类最有害的病原体之一，每年导致数百万人死亡。 2019年，中国湖北省武汉市发生的一组肺炎病例被确定为新型β冠状病毒，其引起的疾病被称为2019冠状病毒病（COVID-19）。 COVID-19 在短短两个多月内迅速演变为全球大流行病。联合国秘书长安东尼奥·古特雷斯认为，世界面临着二战以来最具挑战性的危机，每个国家的人民都面临着一场前所未有的大流行病。通过物理和化学消毒（例如喷洒或擦拭）可以减轻 COVID-19 的传播。然而，消毒是劳动力和材料密集型的，对于覆盖所有暴露区域是不切实际的，并且需要定期重新进行。因此，开发能够缓慢释放消毒化学物质以减轻污染物传播的自消毒表面将是有用的。此类涂层应耐摩擦、耐清洗、持久且无毒，并且应易于涂覆在人们经常触摸的已安装物体的表面上。 该项目的目标是通过将封装的碱性溶液纳入超疏水涂层来探索多功能抗菌和抗病毒涂层。这种涂层可以长期有效地提高抗菌/抗病毒性能，可以保证杀菌剂和杀病毒剂随着时间的推移适当释放，从而大大降低COVID-19疾病的风险。