Towards the determination of the level of dietary phosphorus in high-producing sows

高产母猪日粮磷水平的测定

• 批准号: 527646-2018
• 负责人: LétourneauMontminy, MariePierre
• 金额: $ 2.83万
• 依托单位: Université Laval
• 依托单位国家: 加拿大
• 项目类别: Collaborative Research and Development Grants
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=697562
• 关键词: Towards; determination; level; dietary; phosphorus

The main purpose of this project is to improve the dietary phosphorus (P) metabolism and interfering factors' knowledge to develop a mathematical model representing the fate of dietary P and calcium(Ca) in the sow to optimize their use, better define research priorities and establish dietary P and Ca recommendations. Specifically the objectives are improving sow welfare and longevity and the sustainability of the production by: 1) Adapting the model of the fate of dietary phosphorus and calcium developed in growing pigs to sows. 2) Developing a non-invasive tool to assess bone mineral status based on Ca:P ratio in urine in pigs and sows, 3) Following-up blood markers of bone formation and resorption and Ca and P in blood and urine in relation to production stage (gestation and lactation), 4) Simulate bone reserves remodeling in sows, and 5) Establish optimal P and Ca feeding strategies using the developed model. In comparison to growing pigs low research effort has been given to the sow's mineral requirement because first of the few non-invasive methods available and second, the fact that research costs on sows a major challenge. Mathematical modelling is a powerful tool that simultaneously takes into account all the mechanisms involved in a given system and predicts the relationships that describe its behaviour by integrating the data already published on a subject of study. Such a tool is very powerful in nutrition because it allows a multicriteria approach and the adaptation of recommendations according to the objective of the targeted production objectives. The development of a multicriteria approach integrating the acquired knowledge and new fundamental results, through an experimental trial, a meta-analysis and the development of a mathematical model representing the fate of dietary P and Ca in the sow, will help optimize their use, better defined research priorities and allow the establishment of dietary P and Ca recommendations.

该项目的主要目的是改善日粮磷（P）代谢和干扰因素的知识，开发代表母猪日粮磷和钙（Ca）命运的数学模型，以优化其使用，更好地确定研究重点和建立膳食磷和钙建议。具体目标是通过以下方式改善母猪的福利和寿命以及生产的可持续性： 1) 将生长猪中开发的日粮磷和钙的去向模型应用于母猪。 2) 开发一种非侵入性工具，根据猪和母猪尿液中的 Ca:P 比率来评估骨矿物质状态，3) 跟踪骨形成和吸收的血液标志物以及血液和尿液中与生产相关的 Ca 和 P阶段（妊娠和哺乳期），4) 模拟母猪骨储备重塑，以及 5) 使用开发的模型建立最佳的磷和钙饲喂策略。与生长猪相比，对母猪矿物质需求的研究工作较少，首先是因为可用的非侵入性方法很少，其次是母猪的研究成本是一个重大挑战。数学建模是一种强大的工具，它同时考虑给定系统中涉及的所有机制，并通过集成已发布的研究主题数据来预测描述其行为的关系。这种工具在营养方面非常强大，因为它允许采用多标准方法并根据目标生产目标调整建议。通过实验试验、荟萃分析和开发代表母猪日粮 P 和 Ca 命运的数学模型，开发一种将所获得的知识和新的基本结果相结合的多标准方法，将有助于优化它们的使用，更好地明确研究重点并允许建立膳食磷和钙建议。