Pyrrole Chemistry for Chemical Biology and Energy

化学生物学和能源领域的吡咯化学

• 批准号: CRC-2019-00014
• 负责人: Thompson, Alison
• 金额: $ 14.57万
• 依托单位: Dalhousie University
• 依托单位国家: 加拿大
• 项目类别: Canada Research Chairs
• 财政年份: 2020
• 资助国家: 加拿大
• 起止时间: 2020-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=695179
• 关键词: Pyrrole; Chemistry; Chemical; Biology; Energy

Pyrrole is an attractive component of materials used in studying and treating disease and in the use of light to generate responses that report sensing or enable storage/delivery of energy. Dr. Thompson's research includes the development of sensors to monitor glucose levels in humans, of air-stable enzymes involved in biosynthesis and of materials for redox-flow batteries. It includes generating fundamental knowledge of (poly)pyrroles that emit light from the red into the infrared. Underpinning all of these is the development of practical syntheses of molecules incorporating pyrroles, syntheses which are robust, economical and tolerant of a wide variety of substituents.

吡咯是用于研究和治疗疾病的材料的有吸引力的组成部分，以及使用光来产生报告的反应，以报告或能够储存/传递能量。汤普森（Thompson）博士的研究包括开发传感器，以监测人类中的葡萄糖水平，涉及生物合成的气稳定酶以及用于氧化还原电池的材料。它包括生成（多）吡咯尔的基本知识，这些知识从红色发出的光线散发到红外线。所有这些的基础是结合吡咯，合成的分子实用合成的发展，这些分子，合成的合成稳健，经济且耐受多种取代基。