Molecular characterization of RAS GTPase

RAS GTP 酶的分子表征

• 批准号: 400827
• 负责人: Ohh Michael
• 金额: $ 74.68万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2019
• 资助国家: 加拿大
• 起止时间: 2019-03-01 至 2024-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=400827&lang=en
• 关键词: Phosphorylation; Ras; Signalling

RAS is one of the most frequently mutated cancer-causing genes that govern several cellular processes critical for cancer cell survival and growth. Despite intensive efforts since its discovery over three decades ago, drugs directed against RAS have ultim

RAS 是最常见突变的致癌基因之一，它控制着对癌细胞生存和生长至关重要的多种细胞过程。尽管自三十多年前发现以来经过大量努力，针对 RAS 的药物最终还是取得了成功。