Development of a wireless 8-channel neural monitoring SoC (system on a chip) for integration on a fully-flexible implantable brain-machine interface

开发无线 8 通道神经监测 SoC（片上系统），用于集成在完全灵活的植入式脑机接口上

• 批准号: 531893-2018
• 负责人: Kassiri, Hossein
• 金额: $ 1.82万
• 依托单位: York University
• 依托单位国家: 加拿大
• 项目类别: Engage Grants Program
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=655177
• 关键词: Development; wireless; channel; neural; monitoring

Closed-loop Neuromodulation, which means stimulating the brain using electrical pulses upon detection of a**neurological event, is a well-known method that has been proven to be effective in treatment/control of various**neurological disorders. The efficacy of such a treatment option heavily depends on continuous monitoring of**the brain along with real-time processing of the recorded data to yield an accurate detection. This requires a**highly-miniaturized (ideally implantable) device that integrates the three functions of monitoring, signal**processing, and stimulation, while operating fully wireless to allow for the patient to go about their normal life.**In addition to the electronics, such a device must also integrate recording/stimulation electrodes on the same**platform.**The proposed project will advance the development of implantable EEG acquisition systems by designing**miniaturized electronics for EEG data collection, processing, and wireless transmission. Combined with**specialized electrodes made from biocompatible materials, the overall solution will overcome the limitations of**current instrumentation and allow for widespread use of long-term EEG, resulting in better diagnosis and**management of neurological conditions and leading to improved patient outcomes.

闭环神经调节是一种众所周知的方法，它在检测到**神经系统事件后使用电脉冲刺激大脑，已被证明可以有效地治疗/控制各种**神经系统疾病。这种治疗选项的功效在很大程度上取决于**大脑的连续监测以及对记录数据的实时处理以产生准确的检测。这需要一个高度调整（理想地植入的）设备，该设备整合了监视，信号**处理和刺激的三个功能，同时完全无线操作以允许患者正常生活。电子设备还必须在同一**平台上整合记录/刺激电极。 。结合使用由生物相容性材料制成的**专用电极，总体解决方案将克服**当前仪器的局限性，并允许广泛使用长期脑电图，从而更好地诊断和**对神经系统的治疗，并导致改善的患者结果。