Discovery and Creation of Metal Carbonyl (MC) Supramolecular Chemistry

金属羰基（MC）超分子化学的发现和创造

• 批准号: RGPIN-2016-04497
• 负责人: Wang, Xiaosong
• 金额: $ 1.82万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2016
• 资助国家: 加拿大
• 起止时间: 2016-01-01 至 2017-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=615103
• 关键词: Discovery; Creation; Metal; Carbonyl; MC

Based on Dr Wang’s invention of migration insertion polymerization (MIP) and recent discoveries of metal carbonyl (MC) self-assembled vesicles, MC supramolecular chemistry is proposed. The originality and novelty of the proposed work will lead to new directions of research for several fields, including supramolecular chemistry, organometallic polymer and colloids. With sufficient support, Dr Wang will be an international leader in these fields. Dr Wang discovered that hydrophobic, non-surface active CpPPh3Fe(CO)CO(CH2)5CH3 (FpC6), as an MC building block, can self-assemble in water into uniform vesicles with high membrane integration. The colloids are stabilized via the balance of water-carbonyl interaction (WCI), hydrophobic hydration (HH) and hydrophobic interaction (HI). This aqueous behavior of MCs bears a resemblance to many natural systems, e.g. proteins. MC supramolecular chemistry will therefore offer an experimental system to verify the arbitrary theories for WCI, HH and HI established mainly based on complicated biological systems and computation chemistry. FpC6 is also able to assemble in solid state into the first example of well-characterized supramolecular duplex chains via intermolecular pi-pi interaction and hydrogen bonding with CO as acceptor. This discovery is achieved via reverse crystal engineering. By varying the chemical structure of MCs, assembling conditions and additives, unusual opportunities arise to learn the synergy of multiple interactions that is essential for designed synthesis. The duplex chains, rarely observed, are potentially useful materials with combined properties of macromolecules and locally ordered MC groups, providing new concepts for industrial R & D. MIP allows us to access a novel group of macromolecular MC building blocks, PFpPs and their derivatives. In addition to WCI, HH and HI, the assembly of PFpPs, like proteins, is related to chain conformation and kinetic stability. These two aspects will be studied to assist our understanding of natural systems and develop concepts for bio-mimic materials. PFpP is hydrophobic and also able to assemble into vesicles in water. The vesicular membrane is thin, but highly integrated, with a surface covered with MCs. This unique feature will be explored for potential applications as nanoreactors and scavengers for contaminants in water. This research will: 1) create an experimental system bridging natural assembling systems and supramolecular chemistry; 2) create new concepts for novel materials; 3) advance a number of scientific frontiers, including organometallic polymers, supramolecular chemistry and aqueous colloids; 4) provide a cutting-edge training platform. Canadian science and industry will therefore benefit from the expected world-firsts in knowledge and HQPs behind them.

基于王博士的迁移插入聚合（MIP）发明和金属羰基（MC）自组装囊泡的最新发现，提出了MC超分子化学，该工作的原创性和新颖性将为多个领域的研究带来新的方向。 ，包括超分子化学、有机金属聚合物和胶体，在足够的支持下，王博士将成为这些领域的国际领导者。 王博士发现，疏水性、非表面活性的CpPPh3Fe(CO)CO(CH2)5CH3 (FpC6)作为MC构建块，可以在水中自组装成具有高膜集成度的均匀囊泡，并通过平衡来稳定胶体。 MC 的水-羰基相互作用 (WCI)、疏水水合 (HH) 和疏水相互作用 (HI) 的这种水行为与许多相似。因此，MC超分子化学将提供一个实验系统来验证主要基于复杂生物系统和计算化学建立的WCI、HH和HI任意理论。 FpC6 还能够通过分子间 pi-pi 相互作用和以 CO 作为受体的氢键，以固态组装成第一个表征良好的超分子双链。这一发现是通过改变 MC 的化学结构实现的。 ，组装条件和添加剂，出现了学习多种相互作用的协同作用的不寻常的机会，这对于设计合成至关重要。很少观察到的双链是具有大分子和局部有序组合特性的潜在有用材料。 MC集团，为产业研发提供新理念。 MIP 使我们能够获得一组新型的大分子 MC 构件，即 PFpP 及其衍生物，除了 WCI、HH 和 HI 之外，PFpP 的组装与蛋白质一样，与链构象和动力学稳定性这两个方面有关。研究旨在帮助我们了解自然系统并开发仿生材料的概念。 PFpP 具有疏水性，并且能够在水中组装成囊泡。薄但高度集成，表面覆盖有MC，将探索这种独特的功能作为纳米反应器和水中污染物清除剂的潜在应用。 这项研究将：1）创建一个连接自然组装系统和超分子化学的实验系统；2）创造新材料的新概念；3）推进许多科学前沿，包括有机金属聚合物、超分子化学和水性胶体；因此，加拿大科学和工业将受益于其背后预期的世界第一知识和总部。