Marine Enzymes - Elucidation of their distinct properties and their exploitation for food preservation.

海洋酶 - 阐明其独特特性及其在食品保鲜方面的利用。

• 批准号: 36568-2013
• 负责人: Simpson, Benjamin
• 金额: $ 2.11万
• 依托单位: McGill University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=568751
• 关键词: Marine; Enzymes; Elucidation; their; distinct

This proposal is a request to NSERC for funds to continue and extend our research program with its overall objective focused on investigating novel marine enzymes for potential uses as biotechnological tools for food processing and preservation. This is based on the need for enzymes for both food and non-food uses, such as food texture modification, production of beverages, oil extraction, flavors, dietetic foods, pharmaceuticals, detergents, textiles, biofuels, etc. The global market for enzymes is growing at a rate of about 6%/yr, and is predicted to generate about US$4.4bn by the year 2015. Of this amount, food grade enzymes are forecasted to constitute about 30% (http://www.bccresearch.com/report/enzymes-industrial-applications-bio030f.html). Thus, the enzyme industry is actively seeking novel and dynamic enzymes, and innovative methods to produce them cost-effectively. In this context, the marine ecosystem with its diverse and unique habitats that harbor a myriad of vertebrate, invertebrate and other species represents an excellent pool of unique enzymes that are suitable for applications under a wide range of conditions. The specific objectives of this next phase of our research program are to study digestive enzymes from cuttlefish, squid and cunner fish, and to produce them in high yields in bacteria, for recovery and immobilization into stable and active forms. The enzymes thus produced, will also be investigated for their efficacy to produce bioactive protein hydrolysates and bioactive peptides from food byproducts. These bioactives are being actively sought globally to exploit their beneficial effects such as antioxidant, antimicrobial and enzyme inhibitory properties, in order to reduce the reliance on the use of chemical compounds as food processing aids. There is also global interest to obtain biodegradable films as alternatives to synthetic plastics for food packaging. This program will also prepare biodegradable films from shrimp shells and distillers dry grains, for integration with the bioactive extracts to form novel bioactive films that combine preservation and packaging functions.

该提案是向 NSERC 请求资金，以继续和扩展我们的研究计划，其总体目标侧重于研究新型海洋酶作为食品加工和保存的生物技术工具的潜在用途。这是基于食品和非食品用途对酶的需求，例如食品质地改性、饮料生产、榨油、香料、减肥食品、药品、洗涤剂、纺织品、生物燃料等。全球酶市场每年以 6% 左右的速度增长，预计到 2015 年将产生约 44 亿美元的收入。其中，食品级酶预计将占 30% 左右（http://www.bccresearch.com/report/enzymes-industrial-applications-bio030f.html）。因此，酶行业正在积极寻求新颖、动态的酶，以及经济高效地生产它们的创新方法。在这种背景下，海洋生态系统及其多样化和独特的栖息地，栖息着无数的脊椎动物、无脊椎动物和其他物种，代表了一个优秀的独特酶库，适合在各种条件下应用。 我们研究计划下一阶段的具体目标是研究来自墨鱼、鱿鱼和鲫鱼的消化酶，并在细菌中高产地生产它们，以便回收和固定化为稳定和活性的形式。由此产生的酶还将研究其从食品副产品中生产生物活性蛋白水解产物和生物活性肽的功效。全球正在积极寻找这些生物活性物质，以利用其有益作用，例如抗氧化、抗菌和酶抑制特性，以减少对使用化合物作为食品加工助剂的依赖。全球也对获得可生物降解薄膜作为食品包装合成塑料的替代品感兴趣。该项目还将利用虾壳和酒糟制备可生物降解的薄膜，与生物活性提取物结合，形成兼具保鲜和包装功能的新型生物活性薄膜。