Determining cause and effect: dynamic T cell receptor signaling during thymic selection

确定因果关系：胸腺选择过程中的动态 T 细胞受体信号传导

• 批准号: 320077
• 负责人: Melichar Heather
• 金额: $ 21.86万
• 依托单位: Centre de recherche de l'Hôpital Maisonneuve-Rosemont (Montral)
• 依托单位国家: 加拿大
• 项目类别: Salary Programs
• 财政年份: 2014
• 资助国家: 加拿大
• 起止时间: 2014-12-01 至 2019-12-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=320077&lang=en
• 关键词: Co-Stimulation; Negative Selection; Neonate; Positive Selection; T Cell Tolerance; Thymus; Two-Photon Microscopy; Co-Stimulation; Negative Selection; Neonate; Positive Selection; T Cell Tolerance; Thymus; Two-Photon Microscopy

The immune system is composed of specialized cell types, each of which plays a unique role in combating disease. One of these cell subsets, T cells, develops in the thymus and plays an important function in recognizing, and eliminating, abnormal cells suc

免疫系统由专门的细胞类型组成，每种细胞类型都在打击疾病中起着独特的作用。这些细胞子集之一T细胞在胸腺中发展，并在识别和消除异常细胞中起重要功能