Investigating the Cell Type-Specific Regulatory Role of Ethanol on MeCP2 Expression

研究乙醇对 MeCP2 表达的细胞类型特异性调节作用

• 批准号: 285306
• 负责人: Rastegar Mojgan
• 金额: $ 7.29万
• 依托单位: University of Manitoba
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-04-01 至 2014-04-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=285306&lang=en
• 关键词: Alcohol Exposure And Withdrawal; Brain Cells; Brain Development; Dna Methylation; Epigenetic Control; Fasd; Gene Expression; Gene Regulation; Mecp2 Gene

An environmental factor that causes chronic compromised brain function is maternal alcohol exposure. Prenatal alcohol exposure leads to Fetal Alcohol Spectrum Disorders (FASD). FASD refers to neurological disorders that affect 1-3% of live born children a

导致慢性脑功能损害的环境因素是孕妇酒精暴露。产前酒精暴露会导致胎儿酒精谱系障碍（FASD）。 FASD指的是影响1-3％的活生生儿童的神经系统疾病