Role of the nuclear receptor corepressor-1 in blocking inflammatory gene expression

核受体辅阻遏物-1在阻断炎症基因表达中的作用

• 批准号: 278999
• 负责人: Boudreau François
• 金额: $ 48.2万
• 依托单位: Universit de Sherbrooke
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2013
• 资助国家: 加拿大
• 起止时间: 2013-03-01 至 2018-03-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=278999&lang=en
• 关键词: Cell Culture; Gene Expression Assays; Gene Silencing; Gene Transcription; Inflammatory Bowel Diseases; Mouse Conditional Knockout

Both ulcerative colitis and Crohn's disease represent the major inflammatory diseases (IBD) that affect more than 200,000 youngsters and adults over the country per year. It is thus imperative to better understand genes as well as modifying factors that c

溃疡性结肠炎和克罗恩病都是主要炎症性疾病 (IBD)，每年影响全国超过 200,000 名青少年和成人。因此，必须更好地了解基因以及影响基因的修饰因素。