Training Program in Translational Biology and Molecular Medicine

转化生物学和分子医学培训项目

• 批准号: 9064776
• 负责人: CLIONA M ROONEY
• 金额: $ 41.5万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9064776
• 关键词: Biology; Molecular Medicine; Training Programs

 DESCRIPTION (provided by applicant): This application is for continued support of the Translational Biology and Molecular Medicine (TBMM) graduate program at Baylor College of Medicine (BCM). The TBMM program was founded in 2004 based on the strategic plan of the College to establish new interdisciplinary programs that will drive a new model of integration of biomedical research, clinical patient care and education. The first TBMM class matriculated in 2005 and there are currently 62 students in the program and 33 total graduates. The program counts over 200 participating faculty, of which a core group of 127 are current T32-training faculty. The interdisciplinary faculty members have their primary appointments in 7 clinical and 8 basic science departments and offer research opportunities to T32-trainees in a variety of translational biomedical research areas. The major goal of the TBMM program is to train biomedical PhD scientists to work at the interface of basic and clinical research and more effectively exploit the findings of basic and clinical research to improve human health. To achieve this goal, we have during the prior funding period continue to enhance an established (now in its 9th year) unique PhD program with an innovative curriculum and dual mentorship by a basic science mentor and a clinical mentor of research projects that incorporate biomedical sciences with pathophysiology and medical principles. Although still early since inception, our outcomes data begin to show that we have been successful in recruiting and educating students who graduate with a solid education in basic science, pathophysiology and clinical translational research, prepared to become independent investigators performing translational research at the interface between basic and clinical medicine. Students publish their thesis research in high-impact journals in their respective areas and the program is also promoting interdisciplinary translational research through student-driven collaborations between basic and clinical science mentors. Supported by our growing applicant pool and current student body, we are requesting a total of eight funded positions, an increase from our 6 currently funded positions. Motivated by success of this approach in the prior cycle, we request this funding will again support students in their second and third years of graduate school when they are involved in clinical training as well as pursuing their translational research projects. This funding will allow the TBMM program to continue to mature and graduate translational researchers, who are beginning to make a difference in the field of translational research in academic and non-academic careers. It will also allow us to continue to promote and document ways of effective interaction between basic and clinical investigators and to successfully train a new type of PhD graduate to fill the nationa need to lead future translational research efforts.

 描述（由申请人提供）：本申请旨在继续支持贝勒医学院 (BCM) 的转化生物学和分子医学 (TBMM) 研究生项目 TBMM 项目于 2004 年根据学院的战略计划成立。建立新的跨学科项目，推动生物医学研究、临床患者护理和教育一体化的新模式。第一届 TBMM 班于 2005 年入学，目前有 62 名学生。该项目共有 200 多名毕业生，其中 127 名核心团队是 T32 培训教师，这些跨学科教师主要任职于 7 个临床部门和 8 个基础科学部门，并为 T32 提供研究机会。 - TBMM项目的主要目标是培养生物医学博士科学家在基础和临床研究的交叉领域工作，并更有效地利用基础和临床研究的成果。为了实现这一目标，我们在之前的资助期间继续加强已建立的（现已进入第九个年头）独特的博士项目，该项目具有创新的课程以及由基础科学导师和研究项目临床导师提供的双重指导。将生物医学科学与病理生理学和医学原理相结合，尽管自成立以来还处于早期阶段，但我们的成果数据开始表明，我们已经成功地招募和招收了在基础科学、病理生理学和临床转化研究方面接受过扎实教育的学生，并为他们做好了准备。成为独立调查员执行学生在各自领域的高影响力期刊上发表论文研究，该项目还通过学生驱动的基础科学和临床科学导师之间的合作来促进跨学科转化研究。考虑到申请者群体和当前的学生群体，我们请求总共提供 8 个资助职位，比目前的 6 个资助职位有所增加。受上一周期此方法成功的推动，我们请求这笔资金将再次支持以下领域的学生。 他们在研究生院的第二年和第三年参与临床培训以及开展转化研究项目。这笔资金将使 TBMM 项目能够继续成熟并毕业，开始在该领域有所作为。它还将使我们能够继续促进和记录基础研究人员和临床研究人员之间有效互动的方式，并成功培养新型博士毕业生，以满足国家领导未来转化研究的需要。研究工作。