NURTURE:Research Training and Mentoring Program for Career Development of Faculty at Makerere University College of Health Sciences

培养：麦克雷雷大学健康科学学院教师职业发展研究培训和指导计划

• 批准号: 8987714
• 负责人: Nelson K Sewankambo
• 金额: $ 79.9万
• 依托单位: MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-31 至 2020-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8987714
• 关键词: AIDS/HIV problem; Address; Africa; Africa South of the Sahara; Area; Award; Communicable Diseases; Country; Cryptococcal Meningitis; Development; Disease; Doctor of Philosophy; Environment; Epidemic; Faculty; Fellowship; Focus Groups; Fostering; Funding; Goals; Grant; Guidelines; HIV; Health; Health Priorities; Health Sciences; Health Status; Health system; Human Resources; Incentives; Indigenous; Individual; Infection; Institution; International; Intervention; Investments; Life; Link; Malaria; Master' s Degree; Medical Education; Meningeal Tuberculosis; Mentors; Mentorship; Morbidity - disease rate; Play; Policies; Policy Research; Population; Productivity; Publications; Research; Research Infrastructure; Research Personnel; Research Training; Resources; Role; Scientist; Secure; Services; Stretching; Students; Training; Training Programs; Tuberculosis; Uganda; Universities; Ursidae Family; Vision; antiretroviral therapy; burden of illness; career; career development; co-infection; college; innovation; mortality; programs

 DESCRIPTION (provided by applicant): Sub-Saharan Africa (SSA) bears 24% of the world's burden of disease, the lowest health worker to population ratio and has less than 1% of the global financial resources and 3% of the human resource needs. Globally 35 million people are living with HIV/AIDS, of whom 9.7 million are receiving antiretroviral therapy. HIV/AIDS and related illnesses remain major challenges to health in SSA, where 69% of the global HIV disease burden resides. HIV/AIDS Co-infections including tuberculosis and cryptococcal meningitis remain major causes of morbidity and mortality among HIV-infected individuals. In Uganda, 1.4 million people were estimated to be living with HIV and only 38% are receiving ART according to the 2013 WHO guidelines for ART initiation. The other infectious diseases that have challenged the continent for decades still remain while new ones emerge or old ones re-emerge. Non- communicable diseases (NCDs) are increasingly recognized as emerging epidemics that add an additional burden to our weak health systems already stretched by the ongoing HIV, tuberculosis, malaria and other infectious diseases. Indigenous institutions like Makerere University in Uganda need to play their role in identifying and finding sustainable and easily accessible interventions to the priority national and regional health challenges. Institutios including Makerere University grapple with the inadequate numbers of well-trained researchers particularly at the junior and mid-level. In the last 20-30 years Uganda has made significant advances and substantial contributions to research related to regionally relevant priority health challenges. Some of the research findings have contributed to national and global policies in the areas of HIV/AIDS, tuberculosis (TB) and malaria. Makerere University College of Health Sciences (MakCHS) has played a central role in building Uganda's research capacity. The five-year funding from the Medical Education Partnership (MEPI) grant and its two linked awards (grants # 5R24TW008886, # 5R24TW008861 and # 4R25N5080968) have led to a remarkable further increase in the proportion of publications that have Ugandans as first authors. This demonstrates that the environment is ready for additional investments for research capacity enhancements that will support Ugandan institutions to leapfrog to the next level of research productivity. MakCHS and 4 other Ugandan have trained and mentored 15 PhD students and 68 masters' degree trainees and also supported 29 non-degree mentored faculty research fellowships. There are, however still major gaps in the research capacity of our training institutions required to accelerate improvements in the country's health status. We propose a five year training and mentoring program for junior and mid-level faculty with a particular focus on the three interlinked themes of HIV/AIDS and its associated co-infections, other infectious diseases including malaria, and NCDs. The goal of this proposal is to develop a sustainable culture for supporting research training and mentoring for career development of upcoming faculty in an environment at MakCHS that fosters continuous development and retention of independent researchers. To achieve this goal our program has three specific aims: Aim 1: To provide targeted training and mentorship for individualized research capacity development of junior and mid-level faculty to become independent research leaders capable of addressing regionally relevant health challenges and influence policy and practice. Aim 2: To increase faculty retention by facilitating research career progression through strengthening existing and emerging research groups focusing on HIV/AIDS-related illness, other infectious diseases and NCDs. Aim 3: To facilitate continued development of a conducive research environment at MakCHS with institutional research policies, infrastructure, incentives and services that support researchers to become internationally competitive in conducting high quality research. The proposed capacity building program is to contribute towards the realization of our long term vision for MakCHS to be a leading and transformational institution for academic excellence and innovation in health sciences in Africa. At the end of this 5-year training program, our overarching objective is to solidify research groups of productive, independent scientists who can competitively excel in securing international funding, strengthen the research culture at Makerere and build the capacity to support its partner universities in Uganda. MakCHS is increasingly recognized as a research leader in the area of HIV and associated co-infections, other infections including malaria and the emerging non-communicable diseases.

 描述（由申请人提供）：撒哈拉以南非洲地区 (SSA) 承担着世界 24% 的疾病负担，卫生工作者与人口比例最低，拥有不到全球 1% 的财政资源和 3% 的人力资源需求全球有 3500 万人感染艾滋病毒/艾滋病，其中 970 万人正在接受抗逆转录病毒治疗，艾滋病毒/艾滋病及相关疾病仍然是撒哈拉以南非洲地区健康面临的主要挑战，其中 69% 的人感染艾滋病毒/艾滋病。全球艾滋病毒/艾滋病合并感染（包括结核病和隐球菌性脑膜炎）仍然是艾滋病毒感染者发病和死亡的主要原因。据估计，乌干达有 140 万人感染艾滋病毒，但只有 38% 的人正在接受抗逆转录病毒治疗。根据 2013 年世卫组织关于启动抗逆转录病毒治疗的指南，几十年来一直困扰非洲大陆的其他传染病仍然存在，同时新的非传染性疾病也出现了。人们越来越认识到非传染性疾病是一种新出现的流行病，它给我们本已因艾滋病毒、结核病、疟疾和其他传染病而不堪重负的脆弱卫生系统增加了额外负担。像乌干达麦克雷雷大学这样的土著机构需要在识别和发现疾病方面发挥作用。乌干达在过去 20 至 30 年间，针对国家和地区的重点卫生挑战采取了可持续且易于实施的干预措施，以解决训练有素的研究人员数量不足的问题。麦克雷雷大学健康科学学院 (MakCHS) 的一些研究成果为艾滋病毒/艾滋病、结核病 (TB) 和疟疾领域的国家和全球政策做出了贡献。医学教育伙伴关系 (MEPI) 赠款及其两个相关奖项的五年资助（赠款 # 5R24TW008886、#）在乌干达的研究能力建设中发挥了核心作用。 5R24TW008861 和 # 4R25N5080968）导致乌干达人作为第一作者的出版物比例显着进一步增加，这表明环境已准备好进行额外投资以增强研究能力，这将支持乌干达机构跃升到下一个水平。 MakCHS 和其他 4 名乌干达人培训和指导了 15 名博士生和 68 名硕士学位学员，并为 29 名研究生提供了支持。然而，我们的培训机构在加快改善国家健康状况所需的研究能力方面仍然存在重大差距，我们建议为初级和中级教师提供为期五年的培训和指导计划。特别关注艾滋病毒/艾滋病及其相关合并感染、包括疟疾在内的其他传染病和非传染性疾病这三个相互关联的主题。该提案的目标是发展一种可持续的文化，以支持研究培训和对即将到来的职业发展的指导。环境中的教师MakCHS 致力于促进独立研究人员的持续发展和保留，为了实现这一目标，我们的计划有三个具体目标： 目标 1：为初级和中级教师的个性化研究能力发展提供有针对性的培训和指导，使其成为有能力的独立研究领导者。目标 2：通过加强专注于艾滋病毒/艾滋病相关疾病、其他传染病和非传染性疾病的现有和新兴研究小组，促进研究职业发展，从而提高教师保留率。持续发展一个MakCHS 拥有有利的研究环境，包括机构研究政策、基础设施、激励措施和服务，支持研究人员在开展高质量研究方面具有国际竞争力。拟议的能力建设计划旨在为实现 MakCHS 成为领先者的长期愿景做出贡献。在这个为期 5 年的培训计划结束时，我们的总体目标是巩固研究团队的生产力，以及能够在获得国际资助方面表现出色的独立科学家，加强研究。马凯雷雷文化并建立支持乌干达合作大学的能力，MakCHS 被越来越多地认为是艾滋病毒和相关合并感染、包括疟疾和新出现的非传染性疾病等其他感染领域的研究领导者。