Improved Prenatal Genetic Screening Decision Making through Interactive Technology

通过互动技术改善产前基因筛查决策

基本信息

批准号：
8869498
负责人：
ERIN ROTHWELL
金额：
$ 22.35万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2015
资助国家：
美国
起止时间：
2015-03-06 至 2017-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/8869498
关键词：
Address Age American College of Obstetricians and Gynecologists Arts Child health care Clinic Clinical Collaborations Computers Conflict (Psychology)Couples Decision Making Development Distress Effectiveness Engineering Environment Evaluation Fetus First Pregnancy Trimester Focus Groups Genetic Risk Genetic Screening Genetic screening method Health Healthcare Individual Information Dissemination Interview Knowledge Learning Life Measures Methods Neonatal Screening Outcome Participant Patient Education Patients Population Pregnancy Pregnant Women Prenatal care Process Provider Qualifying Randomized Controlled Trials Recommendation Research Risk Series Site Surveys Technology Testing Time United States National Institutes of Health Universities Utah Woman Work base clinically relevant design ethical legal social implication experience genome sequencing heuristics high risk improved insight novel strategies pregnant prenatal programs prototype public health relevance reproductive satisfaction screening tool usability

项目摘要

DESCRIPTION (provided by applicant): The purpose of this application is to 1) develop a prenatal screening gaming application prototype (PS-GAP) and 2) conduct a preliminary assessment of the PS-GAP on knowledge, satisfaction, and decisional conflict about prenatal genetic screening for pregnant women and their partners. Specific Aim 1: Create a gaming tool for pregnant women and their partners to use to improve knowledge and to assess personal values about prenatal genetic screening. Methods: Develop a prototype in collaboration with gaming experts and clinical experts, leveraging preliminary studies and related work in the healthcare field. The prototype will then be revised in an iterative process with various stakeholder groups. Specific Aim 2: Assess the gaming prototype on knowledge, user satisfaction and decisional conflict about prenatal genetic screening among pregnant women and their partners. Methods: Determine usability and acceptability through both heuristic evaluation and user testing. Pregnant women and the partners will independently engage with the PS-GAP and then compare their choices. All participants will complete post-surveys measuring knowledge, satisfaction and decisional conflict. A sub group will be randomly selected for in-depth interviews about their experiences. Future Research: This R21 will demonstrate feasibility of the development and preliminary utility of a gaming tool on knowledge and decisional conflict related to prenatal genetic screening. Future research will be a multi-site randomized control trial to test the effectiveness of this approach on relevant outcomes including knowledge, distress, and satisfaction with decision-making. Potential Impact: Because of its focus on improved patient decision-making and engagement, this type of tool has widespread application. For example, it can augment other clinically relevant materials throughout pregnancy and be potentially useful in other value-laden genetic testing environments. Research Team: Our team is uniquely qualified to achieve the aims of this study. This application includes collaboration with the University of Utah's Entertainment Arts and Engineering program, one of the top programs in the U.S for game development, and the P20 NIH Utah Center for Excellence in Ethical, Legal and Social Research focused on population screening in prenatal screening and newborn screening in women's and children's health care.

描述（由申请人提供）：本申请的目的是 1) 开发产前筛查游戏应用原型 (PS-GAP)，2) 对 PS-GAP 关于产前的知识、满意度和决策冲突进行初步评估具体目标 1：为孕妇及其伴侣创建一个游戏工具，用于提高有关产前基因筛查的知识并评估个人价值观。方法：与游戏专家合作开发原型。和临床专家们将利用医疗保健领域的初步研究和相关工作，然后与各个利益相关者团体一起对原型进行修订。具体目标 2：评估关于孕妇产前基因筛查的知识、用户满意度和决策冲突的游戏原型。方法：通过启发式评估和用户测试确定可用性和可接受性孕妇和伴侣将独立参与 PS-GAP，然后比较他们的选择。知识、满意度和决策冲突将被随机选择一个小组进行有关他们的经历的深入访谈。未来研究：该 R21 将展示与产前遗传相关的知识和决策冲突的游戏工具的开发和初步实用性。未来的研究将是多地点的。随机对照试验，测试该方法对相关结果（包括知识、痛苦和决策满意度）的有效性：由于其重点是改善患者的决策和参与，此类工具具有广泛的应用。例如，它可以在整个怀孕期间增强其他临床相关材料，并可能在其他有价值的基因测试环境中发挥作用。研究团队：我们的团队具有实现这项研究目标的独特资格。该应用程序包括与犹他大学娱乐部门的合作。艺术与工程项目，顶尖项目之一美国的游戏开发中心和 P20 NIH 犹他州道德、法律和社会研究卓越中心专注于产前筛查中的人口筛查以及妇女和儿童医疗保健中的新生儿筛查。