Improving cochlear implant performance by optimizing bilateral speech processors

通过优化双边语音处理器提高人工耳蜗性能

• 批准号: 8725119
• 负责人: Justin Aronoff
• 金额: $ 15.24万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-08-20 至 2016-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8725119
• 关键词: Acoustics; Apical; Bilateral; Clinic; Clinical; Cochlear Implants; Communication; Cues; Data; Devices; Ear; Electric Stimulation; Electrodes; Environment; Exhibits; Frequencies; Goals; Implant; Location; Masks; Measures; Methods; Noise; Patients; Performance; Population; Research; Signal Transduction; Site; Source; Space Perception; Speech; Time; base; clinically significant; implantation; improved; programs; public health relevance; relating to nervous system; research study; sound

DESCRIPTION (provided by applicant): Bilateral implantation has yielded considerable improvements in cochlear implant (CI) performance. However, bilateral CIs are generally programmed clinically as two independent devices. As a result, the full potential of bilateral implants remains untapped. Multiple electrodes can activate overlapping neural populations and thus cause similar percepts ("perceptual overlap"). Perceptual overlap between ears is critical for perceiving binaural cues, particularly interaural time difference. Bilateral CIs can be optimized to maximize the perceptual overlap of electrodes that are matched-up across ears ("matching"), which is not currently done clinically. Perceptual overlap within each ear can considerably limits CI performance. Bilateral CIs can be optimized to reduce the perceptual overlap between electrodes by dividing the signal across the ears, sending adjacent frequency regions to opposite ears ("interleaving"). With matching, where the same frequency regions are sent to both ears, electrodes that are bilaterally matched need to yield the maximum perceptual overlap. With interleaving, where signals from different frequency regions are sent to opposite ears, such pairings need to be avoided. The benefits of matching versus interleaving may vary across patients, and some patients may receive optimal benefit from combining the two methods over different portions of the electrode array. Our long-term goal is to optimize bilateral stimulation for difficult listening situations. We hypothesize that optimally pairing electrodes across ears will improve the perception of spatial cues. We also hypothesize that minimizing the perceptual overlap within and across ears will provide additional spectral cues. Finally, we hypothesize that combining bilateral matching and interleaving for different cochlear regions will maximize the benefit of bilateral implantation.

描述（由申请人提供）：双侧植入在人工耳蜗（CI）性能方面取得了相当大的改进。然而，双侧 CI 在临床上通常被编程为两个独立的设备。因此，双侧种植体的全部潜力仍未得到开发。多个电极可以激活重叠的神经群，从而引起相似的感知（“感知重叠”）。耳朵之间的感知重叠对于感知双耳线索至关重要，特别是耳间时间差。双侧 CI 可以进行优化，以最大限度地提高跨耳匹配的电极的感知重叠（“匹配”），目前临床上还没有这样做。每只耳朵内的感知重叠会极大地限制 CI 性能。可以优化双边 CI，通过将信号划分到耳朵上，将相邻频率区域发送到相对的耳朵（“交错”），减少电极之间的感知重叠。通过匹配，将相同的频率区域发送到双耳，双边匹配的电极需要产生最大的感知重叠。通过交织，来自不同频率区域的信号被发送到相对的耳朵，需要避免这种配对。匹配与交错的好处可能因患者而异，一些患者可能会通过在电极阵列的不同部分结合这两种方法获得最佳益处。我们的长期目标是优化双边关系 对困难的听力情况进行刺激。我们假设，跨耳电极的最佳配对将改善空间线索的感知。我们还假设，最大限度地减少耳朵内和耳朵之间的感知重叠将提供额外的光谱线索。最后，我们假设将不同耳蜗区域的双边匹配和交错相结合将最大化双边植入的好处。