The contributions of interaurally correlated signals and interaurally symmetric place of stimulation for the binaural auditory system

耳间相关信号和耳间对称刺激位置对双耳听觉系统的贡献

• 批准号: 10550180
• 负责人: Justin Aronoff
• 金额: $ 31.43万
• 依托单位: UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-02-01 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10550180
• 关键词: Acoustics; Address; Auditory; Auditory system; Automobile Driving; Behavioral; Bilateral; Binaural; Characteristics; Chronic; Cochlea; Cochlear Implants; Complex; Cues; Devices; Ear; Electric Stimulation; Electrodes; Environment; Exposure to; Hearing; Lead; Left; Location; Measures; Participant; Perception; Performance; Population; Research; Signal Transduction; Sound Localization; Speech; Techniques; Time; binaural hearing; experience; experimental study; improved; insight; normal hearing; programs; sound

PROJECT SUMMARY / ABSTRACT Binaural hearing provides substantial benefits in complex listening environments, improving the ability to understand speech and providing the ability to localize sounds. However, in order to take advantage of binaural cues, sounds from the two ears need to be integrated (binaural integration). Binaural integration does not fully occur for some populations of listeners, such as cochlear implant (CI) users. Whether, and the degree to which, binaural integration occurs depends on two aspects of the acoustic signal. One aspect is the statistical similarity between the waveforms in the left and right ear (interaural correlation). The second is the symmetry in terms of the place of stimulation in the two ears (physical interaural symmetry). Our overarching hypothesis is that interaural correlation and interaural symmetry both play a role in binaural integration, with interaural correlation also driving adaptation, altering the functional interaural asymmetry to counter the effects of the physical interaural symmetry. The proposed study will manipulate the interaural correlation and interaural symmetry of the signal as well as the cochlear region to which the signals are delivered. These experiments will provide insight into both the functioning of the auditory system and the critical factors to consider when developing device programming techniques for bilateral CI users (Specific Aim 1). While adaptation, reducing the effects of physical interaural asymmetry, has been well documented for pitch-matching tasks, we hypothesize that interaurally correlated signals drive adaptation across the entire binaural auditory system, but the magnitude and/or time-course of the effects differ across different binaural cues. These experiments will provide critical insight into the relative importance of interaurally correlated and physically interaurally symmetric signals for driving adaptation. They will also provide critical guidance as to when it is crucial to address the common issue that bilateral CI users chronically receive interaurally correlated signals at interaurally asymmetric locations (Specific Aim 2). The proposed studies will provide fundamental insight in to how the binaural auditory system combines signals from the two ears. This research will also provide insight into the factors that will influence bilateral CI users’ binaural abilities, both directly after activation, and over time. This will lay the groundwork for a paradigm shift in terms of how and when clinicians program bilateral CI users’ devices to maximize binaural benefits.

项目概要/摘要 双耳听力在复杂的聆听环境中提供了巨大的好处，提高了 然而，为了利用双耳，理解语音并提供定位声音的能力。 提示，来自两个耳朵的声音需要集成（双耳集成不需要）。 某些听众群体（例如人工耳蜗 (CI) 用户）是否完全发生，以及发生的程度。 其中，双耳整合的发生取决于声学信号的两个方面，一方面是统计。 左右耳波形的相似性（耳间相关性）。 就两耳的刺激位置而言（耳间的物理对称性）。 假设是耳间相关性和耳间对称性都在双耳整合中发挥作用， 耳间相关性也推动适应，改变功能性耳间不对称性以抵消影响 的物理耳间对称性。 拟议的研究将操纵信号的耳间相关性和耳间对称性以及 这些实验将深入了解信号传递到的耳蜗区域。 听觉系统的功能以及开发设备编程时要考虑的关键因素 双边 CI 用户的技术（具体目标 1），同时适应，减少物理耳间的影响。 不对称性，对于音高匹配任务已有充分记录，我们追求的是耳间相关性 信号驱动整个双耳听觉系统的适应，但是信号的幅度和/或时间过程 不同双耳线索的效果有所不同，这些实验将为相关相关问题提供重要的见解。 耳间相关和物理耳间对称信号对于驱动适应的重要性。 还将就何时必须解决双边 CI 用户的共同问题提供重要指导 长期在耳间不对称位置接收耳间相关信号（具体目标 2）。 拟议的研究将为双耳听觉系统如何组合信号提供基本见解 这项研究还将深入了解影响双边 CI 用户的因素。 双耳能力，无论是在激活后还是随着时间的推移，这都将为范式转变奠定基础。 就如何以及何时对双边 CI 用户的设备进行编程以最大限度地提高双耳效益而言。