Development of a Clinically Viable Pattern Recognition Embedded System

临床上可行的模式识别嵌入式系统的开发

• 批准号: 8935636
• 负责人: Blair Lock
• 金额: $ 50.97万
• 依托单位: COAPT, LLC
• 依托单位国家: 美国
• 财政年份: 2013
• 资助国家: 美国
• 起止时间: 2013-05-01 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8935636
• 关键词: Adopted; Agonist; Algorithms; Amputees; Appearance; Artificial Arm; Back; Benchmarking; Bionics; Boston; Caring; Chicago; Clinic; Clinical; Complex; Computer software; Contracts; Data; Development; Devices; Disabled Persons; Documentation; Elbow; Elements; Engineering; Fostering; Freedom; Future; Goals; Grant; Hand; Health; Home environment; Hour; Impairment; Institutes; Intellectual Property; Joints; Knowledge; Laboratories; Licensing; Limb Prosthesis; Measures; Medicine; Mission; Motion; Muscle; Myoelectric prosthesis; Outcomes Research; Pathway interactions; Patient Education; Patients; Pattern; Pattern Recognition; Persons; Phase; Physical Medicine; Population; Process; Productivity; Prosthesis; Protocols documentation; Public Health; Quality Control; Quality of life; Rehabilitation Research; Rehabilitation therapy; Research; Research Personnel; Signal Transduction; Site; Staging; System; Techniques; Technology; Testing; Time; Touch sensation; Training; Upper Extremity; Work; Wrist; arm; base; clinical application; clinical research site; design; digital; disability; flexibility; graphical user interface; improved; improved functioning; limb amputation; myoelectric control; novel; powered prosthesis; prosthetic hand; public health relevance; reinnervation; research clinical testing

DESCRIPTION (provided by applicant): Pattern recognition (PR) myoelectric control systems can dramatically improve an amputee patient's control of a powered prosthesis, but they have not been made commercially available. Coapt, LLC, is a start-up stage company that has initiated a controlled commercial release of PR myoelectric control for the benefit of upper- limb amputees. The controller is based on research completed by the Center for Bionic Medicine at the Rehabilitation Institute of Chicago (RIC) and has been widely developed and tested with transradial and higher-level amputees. Coapt has previously licensed valuable PR controller technology and intellectual property from the RIC. Upper-limb amputees are faced with significant impairment and have not previously benefitted from the advances in PR control technology. Conveniently, commercially available multifunction prostheses are now available that offer users multiple powered options but these are not presently enabled with PR control. The long-term goal is to provide upper-limb amputees with a more intuitive option for controlling their externally powered prostheses. The objective of this application is to make the initially released commercial product intuitive enough that it can reliably work across a variety of sites and manufactures with minimal on-site engineering time. Coapt's first product is an advanced PR microcontroller system that can 'drive' any existing or future prosthetic arm system by interpreting electromyographic (EMG) signal patterns. An important factor in the development of such a broad reaching approach is reaching as many amputee patients as possible. To achieve consumer acceptance, the product offering must be realized according to the needs and practices of the prosthetic practitioner. This application comprises the following three specific aims: (1) develop a clinically focused software package; (2) complete in laboratory testing of commercially available multifunction arm systems; and (3) evaluate quantitative data regarding the fitting process and resulting prosthesis usage in take- home settings across multiple sites. Under the first aim the clinician-facing elements of the system's configuration software will be implemented with iterative clinical evaluations. Under the second aim, the PR controller system will be configured to enhance the control of commercially available multifunction hand prostheses on amputee subjects. The third aim will provide valuable information that we can compare against bench-mark data from conventional control usage, which in turn will inform future design decisions. The proposed research is significant because it enables a pathway to connect pattern recognition-based myoelectric control with commercially available multifunction prostheses from being adopted. Ultimately, this research will help upper-limb amputees to dramatically improve the control of their prostheses, allowing for an improved quality of life and promote return to work in many cases.

描述（由申请人提供）：模式识别（PR）肌电控制系统可以显着改善截肢患者对动力假肢的控制，但它们尚未商业化。 Coapt, LLC 是一家初创阶段公司，已启动 PR 肌电控制的受控商业发布，以造福上肢截肢者。该控制器基于芝加哥康复研究所 (RIC) 仿生医学中心完成的研究，并已在经桡动脉和更高级别截肢者中进行了广泛开发和测试。 Coapt 此前已从 RIC 获得了宝贵的 PR 控制器技术和知识产权的许可。上肢截肢者面临着严重的损伤，并且之前没有从 PR 控制技术的进步中受益。方便的是，现在市售的多功能假肢可以为用户提供多种动力选项，但目前这些假肢还不能通过 PR 控制来实现。长期目标是为上肢截肢者提供更直观的选择来控制其外部动力假肢。该应用程序的目标是使最初发布的商业产品足够直观，使其能够以最短的现场工程时间跨各种站点和制造商可靠地工作。 Coapt 的首款产品是先进的 PR 微控制器系统，可以通过解释肌电图 (EMG) 信号模式来“驱动”任何现有或未来的假肢系统。发展这种广泛的覆盖方法的一个重要因素是覆盖尽可能多的截肢患者。为了获得消费者的认可，产品供应必须根据假肢从业者的需求和实践来实现。该应用程序包括以下三个具体目标：（1）开发一个以临床为重点的软件包； (2) 完成商用多功能臂系统的实验室测试； (3) 评估有关装配过程的定量数据以及在多个地点的带回家环境中所产生的假肢使用情况。在第一个目标下，系统配置软件的面向临床医生的元素将通过迭代临床评估来实现。在第二个目标下，PR控制器系统将被配置为增强对截肢受试者的市售多功能手假肢的控制。第三个目标将提供有价值的信息，我们可以将其与传统控制使用的基准数据进行比较，从而为未来的设计决策提供信息。这项研究意义重大，因为它提供了一条将基于模式识别的肌电控制与商用多功能假肢连接起来的途径。最终，这项研究将帮助上肢截肢者显着改善对假肢的控制，从而提高生活质量，并在许多情况下促进重返工作岗位。