Heme Oxygenase-1 Inhibition of Hepatitis C Replication

血红素加氧酶 1 抑制丙型肝炎复制

• 批准号: 8195610
• 负责人: WARREN N SCHMIDT
• 金额: --
• 依托单位: IOWA CITY VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-04-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195610
• 关键词: Alcohol abuse; Antioxidants; Antiviral Agents; Antiviral Therapy; Attenuated; Basic Science; Bilirubin; Biliverdine; Carbon Monoxide; Caring; Cells; Chronic; Chronic Hepatitis; Chronic Hepatitis C; Cirrhosis; Data; Defense Mechanisms; Development; Down-Regulation; Enzymes; Equilibrium; Foundations; Genotype; Goals; Healthcare; Heme; Hemin; Hemostatic function; Hepatic; Hepatitis C; Hepatitis C virus; Hepatocyte; Human; In Vitro; Incidence; Individual; Inflammation; Injury; Interferon-alpha; Interferons; Iron; Knowledge; Laboratories; Length; Life Cycle Stages; Liver; Liver diseases; Maintenance; Mediator of activation protein; Metabolic; Modality; Morbidity - disease rate; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxygenases; Patients; Peroxides; Pharmaceutical Preparations; Population; Porphyrias; Prevention; Primary carcinoma of the liver cells; Reaction; Recurrence; Relapse; Replicon; Reporting; Research; Research Support; Ribavirin; Role; Sampling; Staging; Stress; Superoxides; Testing; Therapeutic; Time; Transcriptional Regulation; United States; Veterans; Viral; Virus; Virus Diseases; Virus Replication; Work; base; chronic liver disease; cohort; effective therapy; established cell line; global health; heme oxygenase-1; in vivo; interest; interferon therapy; liver transplantation; mortality; novel; novel strategies; overexpression; prevent; public health relevance; research study; response