Bioinformatics Inquiry through Sequencing (BIOSEQ)

通过测序进行生物信息学查询（BIOSEQ）

• 批准号: 8877366
• 负责人: DAVID R. WALT
• 金额: $ 25.53万
• 依托单位: TUFTS UNIVERSITY MEDFORD
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-06-01 至 2016-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8877366
• 关键词: Bioinformatics; Biology; Chemistry; Communities; Computers; Data Analyses; Development; Educational process of instructing; Equipment; Faculty; Genetic; Genetic screening method; Genome; Genomics; Goals; Health; High School Faculty; High School Student; Individual; Knowledge; Laboratories; Learning; Medical Research; Participant; Play; Process; Public Health; Reagent; Research; Research Proposals; Role; Scholarship; Schools; Science; Students; Testing; Underrepresented Minority; Universities; base; career; college; community college; computer science; design; experience; genome wide association study; graduate student; high school; innovation; low socioeconomic status; microbial; outreach; personalized medicine; programs; research study; skills; teacher; tool; undergraduate student; university student

DESCRIPTION (provided by applicant): The overall goal for the Bioinformatics Inquiry through Sequencing (BIOSEQ) project is to provide opportunities for a broad audience of people to learn about the field of bioinformatics through inquiry based research. Three main activities will support this goal: 1. Increase knowledge of and participation in inquiry-based bioinformatics research among students and educators by establishing a sequencing center at Tufts University's Medford Campus for educational use. This sequencing center will be available to college students and high school students through college level research courses and will also be available to educators and students who wish to integrate sequencing into classroom projects, science fair projects, college level theses and graduate level research through an application process. 2. Introduce bioinformatics to college students and high school students through entry level, semester-long research-based courses designed to teach students laboratory skills, computer skills and research skills in the context of student designed projects. The high school student course will happen during the summer session, students will be able to receive college credit. Scholarships will be available for underrepresented minorities and those of low socioeconomic status to participate in the course. 3. Increase teacher knowledge of bioinformatics and inclusion of bioinformatics concepts in their courses by developing modular activities and curricular units to describe bioinformatics concepts, including the impact of bioinformatics on scientific and medical research. Some of these activities and units will be integrated into existing high school biology and computer science courses, and will include understanding of how bioinformatics and genomics have influenced individual and public health through innovations such as Genome Wide Association studies (GWAs) and Direct to Consumer (DTC) genetic testing. This five year project will involve faculty, staff, graduate students, and undergraduate students from Tufts' Chemistry and Computer science departments, faculty and students from Bunker Hill Community College, and teachers and high school students from four diverse, urban partner school districts.

描述（由申请人提供）：通过测序进行生物信息学探究（BIOSEQ）项目的总体目标是为广大受众提供通过基于探究的研究了解生物信息学领域的机会。三项主要活动将支持这一目标： 1. 通过在塔夫茨大学梅德福校区建立一个用于教育用途的测序中心，增加学生和教育工作者对基于探究的生物信息学研究的了解和参与。 该测序中心将通过大学水平的研究课程向大学生和高中生开放，也将向希望通过应用程序将测序融入课堂项目、科学博览会项目、大学水平论文和研究生水平研究的教育工作者和学生开放。过程。 2. 通过入门级、为期一个学期的研究型课程，向大学生和高中生介绍生物信息学，这些课程旨在教授学生在学生设计的项目中的实验室技能、计算机技能和研究技能。 高中生课程将在暑期进行，学生将能够获得大学学分。将为代表性不足的少数群体和社会经济地位较低的人提供奖学金来参加该课程。 3. 通过开发模块化活动和课程单元来描述生物信息学概念，包括生物信息学对科学和医学研究的影响，增加教师的生物信息学知识并将生物信息学概念纳入其课程。 其中一些活动和单元将整合到现有的高中生物学和计算机科学课程中，并将包括了解生物信息学和基因组学如何通过全基因组关联研究 (GWA) 和直接面向消费者 (GWA) 等创新影响个人和公共健康。 DTC）基因检测。 这个为期五年的项目将涉及塔夫茨大学化学和计算机科学系的教职员工、研究生和本科生、邦克山社区学院的教职员工和学生，以及来自四个不同的城市合作学区的教师和高中生。