OBTAIN TISSUES AND ORGANS FOR HIV RESEARCH

获取用于艾滋病毒研究的组织和器官

• 批准号: 8356907
• 负责人: JOHN T LONSDALE
• 金额: $ 17.92万
• 依托单位: NATIONAL DISEASE RESEARCH INTERCHANGE
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-07-01 至 2012-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8356907
• 关键词: Collection; Communities; Computer Hardware; Computer software; Data; Destinations; Ensure; Eye Banks; Funding; Goals; Grant; HIV; HIV Seropositivity; Health; Hospitals; Human; Information Systems; National Center for Research Resources; Organ; Organ Procurements; Pathology; Preparation; Principal Investigator; Protocols documentation; Research; Research Infrastructure; Research Personnel; Research Project Grants; Resources; Scientist; Shipping; Ships; Site; Source; Specific qualifier value; System; Tissue Banking; Tissue Banks; Tissue Preservation; Tissues; United States National Institutes of Health; Work; arm; cost; data management; human tissue; improved; programs; surgical service; web site

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. Primary support for the subproject and the subproject's principal investigator may have been provided by other sources, including other NIH sources. The Total Cost listed for the subproject likely represents the estimated amount of Center infrastructure utilized by the subproject, not direct funding provided by the NCRR grant to the subproject or subproject staff. DESCRIPTION (provided by applicant): The Human Tissues and Organs for Research (HTOR) program of the NDRI is dedicated solely to accessing and providing human tissues for research purposes. These tissues and organs are essential for the great majority of research projects served by HTOR and the program is clearly relevant to advancing human health. HTOR's long-term objective is to increase the quantity, diversity, and quality of human research tissues available for research. The collection, preparation, and preservation of the tissues must be performed according to researcher-specified protocols for the materials to be useful to scientists. The acquisition of these materials requires an extensive national network of acquisition sites such as hospital pathology and surgical services, eye and tissue banks, and Organ Procurement Organizations. HTOR's unique systems ensure that tissues procured for customized protocols are delivered in a timely manner to the appropriate research destinations. The quantity, quality and diversity of tissues shipped to investigators is a function of three critical variables: the number and types of sources working with HTOR, the internal systems of HTOR, and the number and types of research requests that HTOR receives from researchers. The specific aims of the proposed funding period focus on strengthening these three arms of the HTOR program (sources, information systems, and researchers). HTOR will work to increase the capabilities of existing sources and add new sources to increase tissue quantity and diversity (Specific Aim 1/Sources); upgrade HTOR's internal systems (computer hardware, software, and data management) to improve data capture and analysis, and upgrade the HTOR Web Site to increase Source and Researcher access to HTOR resources (Specific Aim 2/Systems); and work closely with the research community to fulfill existing and emerging needs for human research tissue (Specific Aim 3/Researchers). In addition, HTOR will continue a specialized program for procuring and distributing HIV positive tissues (Specific Aim 4), a goal that is also consistent with HTOR's long-term objective.

该子项目是利用资源的众多研究子项目之一 由 NIH/NCRR 资助的中心拨款提供。子项目的主要支持 并且子项目的主要研究者可能是由其他来源提供的， 包括其他 NIH 来源。 子项目可能列出的总成本 代表子项目使用的中心基础设施的估计数量， NCRR 赠款不直接向子项目或子项目工作人员提供资金。 描述（由申请人提供）： NDRI 的人体组织和器官研究 (HTOR) 计划专门致力于获取和提供用于研究目的的人体组织。 这些组织和器官对于 HTOR 服务的绝大多数研究项目至关重要，该项目显然与促进人类健康相关。 HTOR 的长期目标是增加可用于研究的人类研究组织的数量、多样性和质量。 组织的收集、准备和保存必须按照研究人员指定的方案进行，以使材料对科学家有用。 这些材料的采购需要广泛的全国采购地点网络，例如医院病理和外科服务、眼科和组织库以及器官采购组织。 HTOR 独特的系统确保为定制方案采购的组织及时运送到适当的研究目的地。 运送给研究人员的组织的数量、质量和多样性取决于三个关键变量：与 HTOR 合作的来源的数量和类型、HTOR 的内部系统以及 HTOR 从研究人员那里收到的研究请求的数量和类型。 拟议资助期的具体目标侧重于加强 HTOR 计划的这三个部门（来源、信息系统和研究人员）。 HTOR 将努力提高现有来源的能力并添加新来源以增加组织数量和多样性（具体目标 1/来源）；升级 HTOR 的内部系统（计算机硬件、软件和数据管理）以改进数据捕获和分析，并升级 HTOR 网站以增加来源和研究人员对 HTOR 资源的访问（具体目标 2/系统）；并与研究界密切合作，以满足人类研究组织的现有和新兴需求（具体目标 3/研究人员）。 此外，HTOR 将继续实施采购和分发 HIV 阳性组织的专门计划（具体目标 4），这一目标也与 HTOR 的长期目标一致。