Multi-scale Complex Systems Transdisciplinary Analysis of Response to Therapy (MC

治疗反应的多尺度复杂系统跨学科分析（MC

• 批准号: 7942786
• 负责人: William Daniel Hillis
• 金额: $ 314.4万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-28 至 2014-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7942786
• 关键词: Acute; Acute Myelocytic Leukemia; Adjuvant; Advanced Malignant Neoplasm; Advisory Committees; Affect; Alternative Therapies; Antineoplastic Agents; Behavior; Belief; Benchmarking; Biological Models; Businesses; Cancer Model; Cell model; Clinical; Commit; Community Outreach; Complex; Data Set; Development; Disabled Persons; Disease; Disease remission; Disease-Free Survival; Drug Delivery Systems; Drug resistance; Education; Education and Outreach; Effectiveness; Elements; Encapsulated; Ensure; Environment; Evolution; Funding; Genes; Genetic; Genetic Risk; Genotype; Growth; Hematologic Neoplasms; Hematopoietic Neoplasms; Heterogeneity; Human; Hypoxia; Immune; Individual; Institution; Lead; Left; Liquid substance; Malignant Neoplasms; Measurement; Measures; Metabolic; Methods; Modeling; Molecular; Molecular Evolution; Mutation; Neoplasms in Vascular Tissue; Non-Hodgkin' s Lymphoma; Oncologist; Organism; Outcome; Patients; Physiological; Pilot Projects; Population; Postdoctoral Fellow; Property; Recommendation; Recording of previous events; Regimen; Relapse; Relative (related person); Reporting; Research Personnel; Resistance; Resolution; Sampling; Scientist; Series; Serum Proteins; Signal Transduction; Simulate; Solid; Staging; Structure; System; Techniques; Testing; Therapeutic; Time; Validation; Vision; Woman; Work; base; cancer cell; cancer genetics; cancer therapy; chemotherapeutic agent; chemotherapy; clinically relevant; cytotoxic; drug sensitivity; handicapping condition; improved; leukemia; malignant breast neoplasm; meetings; member; molecular scale; neoplastic cell; novel; oncology; physical science; programs; response; simulation; standard of care; tool; tumor; tumor growth; virtual; web site

DESCRIPTION (provided by applicant): The Administrative Core (AC) will function to manage the CAC and help administer and support the PSOCMC- SMART. The will help coordinate the CAC twice monthly meetings. The CAC, together with the program manager, will assure that project and core plans progress, postdoctoral fellows are shared, training and outreach efforts are implemented, pilot projects are encouraged and funded, and the 'business' of the program is accomplished. A key element of the AC will be a full time program manager who will work closely with Drs. Hillis as well the other members of the Center Advisory Committee to help execute all recommendations of the CAC, NCI Project Scientist and the PSC. The AC will assure that all meeting generated notes/reports to the CAC and PSC are prepared and disseminated. Additionally, as both integrative education and community outreach are such significant portions of the PSOC-MC-START program, the AC will be managing the PSOC-MC-SMART website and the implementation of the PSOC-MCSTART member ectures/seminars in both the i) newly planned series, and the ii) leveraged series at our collaborating institutions, and professional association meetings, to educate about physical sciences and oncology.

描述（由申请人提供）：管理核心 (AC) 将负责管理 CAC 并帮助管理和支持 PSOCMC-SMART。这将帮助协调 CAC 每月两次的会议。 CAC 与项目经理将确保项目和核心计划的进展、博士后研究员的共享、培训和推广工作的实施、试点项目的鼓励和资助以及项目的“业务”的完成。 AC 的一个关键要素将是一名全职项目经​​理，他将与 Drs 密切合作。 Hillis 以及中心咨询委员会的其他成员帮助执行 CAC、NCI 项目科学家和 PSC 的所有建议。 AC 将确保准备并分发向 CAC 和 PSC 提交的所有会议记录/报告。此外，由于综合教育和社区外展都是 PSOC-MC-START 计划的重要组成部分，AC 将管理 PSOC-MC-SMART 网站以及在两个领域实施 PSOC-MCSTART 成员讲座/研讨会。 ) 新计划的系列，以及 ii) 在我们的合作机构和专业协会会议上利用系列，以教育物理科学和肿瘤学。